Fundacio Privada Universitat I Tecnologia

Pneumococcal disease is a major cause of morbidity, hospitalization and mortality. Two age groups show a greater incidence and severity of the disease: children under the age of 5 years (mainly during the first 2 years of life) and adults aged more than 65 years. The heptavalent pneumococcal conjugate vaccine, which was commercialized in Spain in June 2001, is efficacious in children aged less than 2 years and, unlike the non-conjugate 23-valent vaccine, it induces immunological memory. In Spain the heptavalent vaccine covers 80 % of serotypes causing pneumococcal invasive disease and acute otitis media in children aged 2-59 months. The heptavalent vaccine has been shown to be immunogenic, efficacious and safe. It has proven efficacy in the prevention of invasive disease caused by the seven vaccine serotypes. In addition, it significantly decreases pneumonia and also prevent acute otitis media. The vaccine is preferably indicated in children aged less than 2 years; children aged 2-5 years may also benefit from the vaccine but those in risk groups should be prioritized. Greater knowledge of the epidemiology of pneumococcal disease and the efficiency of this vaccine in Spain will determine whether it should be included in the immunization schedule.

Abstract New compounds as potential poly(vinyl chloride) plasticizers based on soybean oil and oligoesters of adipic acid and different glycols by one‐pot transesterification are synthesized. In the first step of the plasticizer synthesis oligoesters of adipic acid and diethylene glycol, triethylene glycol, or dipropylene glycol are synthesized, and then in situ in the second step, a defined amount of soybean oil is introduced. By degradation of soybean oil with oligoesters, and transesterification reaction, different compounds are obtained. Their physicochemical properties are determined by NMR, SEC, DSC, TGA, and volatility analyses. The properties of synthesized plasticizers are compared with commercial products: monomeric (DEHP) and aliphatic oligoster of adipic acid and 1,3‐butanediol (H‐1).

This study presents a novel framework leveraging the potential of Artificial Intelligence (AI) in enhancing the efficacy of Computer Security Incident Response Teams (CSIRTs). It advocates the synergy of AI and open-source resources, tailored to provide robust, case-specific, and flexible solutions. The framework emphasizes the role of AI-based prediction models and anomaly detection techniques in accelerating incident response, increasing threat detection accuracy, and reducing false positives. Additionally, it elucidates the challenges of AI integration into existing CSIRT operations and offers guidance for seamless assimilation. In conclusion, this study posits the availability of cost-effective, auditable, scalable, and custom-fit open-source solutions for AI implementation, with trans-formative potential for CSIRT practice and incident response optimization.

A 35-year-old man with hyperthyroidism reported the sudden occurrence of ulcerated and painful oral lesions, painful ulcerative-necrotic lesions on the face, trunk, upper and lower limbs and purpuric circinate lesions on the scalp, 6 days after starting the treatment with oral iodine. The clinical history, cutaneous-mucosal lesions, and histopathological findings support the diagnosis of iododerma secondary to oral iodine treatment. Iododerma is a rare disease caused by iodine exposure that can develop after oral or intravenous use, rarely after topical use of iodine and is often associated with systemic manifestations related to vasculitis, which can be fatal, as in the present case.

This work presents a power-efficient solution based on Power over Fiber technology that combines and enables the use of electronic devices in fiber optic networks. The optical carrier is modulated via a microelectromechanical variable optical attenuator, using the processed sensor data, which is encoded in a frequency shift keying technique. To illustrate the concept, a 50-km remote environmental station is powered by energy harvesting techniques to provide the requisite power, and a low-power microcontroller encodes the data from electronic sensors. The data was successfully retrieved, achieving data rates of up to 1.5 kbps.

Descubrir la ciudad en el teatro y el teatro en la ciudad a partir de la observación del mapa es el objetivo principal de este trabajo. A lo largo de la historia, la relación del teatro, de los teatros, y en sentido amplio de los espacios escénicos con la ciudad, ha adoptado formas diversas que una cartografía puede reflejar y ayudar a interpretar. Este artículo se centra en el estudio del papel de los edificios dedicados a las artes escénicas en las transformaciones de las ciudades de España. Nuestro enfoque abre un amplio panorama en el que se integran la ciudad, la arquitectura y el teatro, y en el que se observa con un grado de aproximación diverso el dónde, el qué, el cómo y el cuándo del hecho teatral. El espacio y el tiempo constituyen el trasfondo de nuestro análisis.

A crítica à noção de desenvolvimento pode ser arredondada quando os pensamentos periféricos, ou com a capacidade de incorporá-lo como uma exterioridade, lograram revelar os segredos (espaciais) da lógica global do capital. Das primeiras formulações entre os anos 1950 e 1970 até as posteriores houve um salto qualitativo com um discurso capaz de explicar tanto as críticas do desenvolvimento da técnica, bem como do determinismo e do progresso; também passou da crítica do capitalismo à modernidade/pos-modernidade, das tecno-ciências e da complexidade. O que há de permeio neste avanço explicativo (localização da agência enunciativa de “dentro” do desenvolvimento para “fora” da modernidade, é um interregno de hegemonia neoliberal que agora figura como uma crise na dominação que se posicionou como cataclismo e catástrofe (os macro-incêndios regionais em várias esquinas do mundo e a crise pandêmica global são apenas sintomas em série). Talvez hoje estejamos diante de uma das principais características do início do século XXI devido à inédita persistência das transformações climáticas, da biodiversidade ecológica do mundo que acompanha o ansiado crescimento dos índices de lucro econômico no quadro da acumulação global do neoliberalismo. A tendência a buscar na temporalização econômica a criação de espaço (s) se torna um vetor indicativo e orientador, sempre que os limites físico-materiais, geográficos, possam se precipitar como marco definidor ou mesmo bloquear a acumulação mesma. Se não encontrar alternativas a esses dilemas estaremos em perigo iminente de que a crise do capitalismo se modifique (e perversamente procure suas soluções) na crise da humanidade.

This study investigated the anaerobic biodegradation of coffee production waste as a method for producing a high-quality biofertilizer. The resulting digestate was characterized in terms of trace element concentrations, amino acid profile, phytohormone and fulvic acid content, microbiological composition, and heavy metal levels. Bioindication experiments were conducted using ryegrass (Lolium perenne L.), a category I monocotyledonous indicator plant. Dark gray podzolized soil, digestate, and a natural sorbent (natural zeolite from the Sokyrnytskyi deposit) were used as experimental substrates. Comprehensive quality assessment demonstrated that the digestate meets the criteria for a high-quality organic fertilizer, exhibiting a rich chemical composition and environmentally safe properties. The highest mean values of plant growth and development parameters were recorded in treatments containing zeolite, indicating a synergistic effect of digestate and zeolite application on plant performance.

This paper summarises an interview with a former typefounder from Fundición Tipográfica Neufville (1885–1995); the first of a series of interviews with former employees of the firm. It should be considered within the context of a long-term research project that seeks a thorough understanding of the working documents, practices and routines of type-related crafts. Here we aim to capture some key aspects of both the project and the interview: a work-in-progress, combining fundamentals of the discipline, oral history, and personal anecdotes. The presentation will showcase excerpts from the interview.

This paper summarises an interview with a former typefounder from Fundición Tipográfica Neufville (1885–1995); the first of a series of interviews with former employees of the firm. It should be considered within the context of a long-term research project that seeks a thorough understanding of the working documents, practices and routines of type-related crafts. Here we aim to capture some key aspects of both the project and the interview: a work-in-progress, combining fundamentals of the discipline, oral history, and personal anecdotes. The presentation will showcase excerpts from the interview.