General Electric (Germany)

A general expression which can be used either for predicting the average volumetric concentration or for analyzing and interpreting experimental data is derived. The analysis takes into account both the effect of nonuniform flow and concentration profiles as well as the effect of the local relative velocity between the phases. The first effect is taken into account by a distribution parameter, whereas the latter is accounted for by the weighted average drift velocity. Both effects are analyzed and evaluated. The results predicted by the analysis are compared with experimental data obtained for various two-phase flow regimes, with various liquid-gas mixtures in adiabatic, vertical flow over a wide pressure range. Good agreement with experimental data is shown.

Abstract The results of a study of cyclic strain and fatigue failure arising from cyclic thermal stresses are reported. By means of a test apparatus described in a companion paper, a cyclic temperature is imposed on a thin tubular test specimen subjected to complete longitudinal constraint. Hence, the cyclic strain is the independent variable. The following studies are reported: (a) Effect of thermal-stress cycling on strain hardening and life-to-failure for a fixed mean temperature, (b) effect of degree and kind of previous cold work on strain hardening and cycles-to-failure, (c) effect of mean temperature on thermal-stress cycling, (d) effect of period of cycle on cycles-to-failure, and (e) effect of prior strain cycling on stress-strain characteristics. The significance of factors such as hysteresis, Bauschinger effect, strain hardening, strain aging, and fatigue-crack formation is discussed, and a mechanism is described to relate these factors. Evidence is presented to show that strain hardening is not an important factor in the problem. The concept of total plastic strain is discussed.

Event-triggered control consists of closing the feedback loop whenever a predefined state-dependent criterion is satisfied. This paradigm is especially well suited for embedded systems and networked control systems since it is able to reduce the amount of communication and computation resources needed for control, compared to the traditional periodic implementation. In this paper, we propose a framework for the event-triggered stabilization of nonlinear systems using hybrid systems tools, that is general enough to encompass most of the existing event-triggered control techniques, which we revisit and generalize. We also derive two new event-triggering conditions which may further enlarge the inter-event times compared to the available policies in the literature as illustrated by two physical examples. These novel techniques exemplify the relevance of introducing additional variables for the design of the triggering law. The proposed approach as well as the new event-triggering strategies are flexible and we believe that they can be used to address other event-based control problems.

Much has been written about the relationship between high medical expenses and the likelihood of filing for bankruptcy, but the relationship between receiving a cancer diagnosis and filing for bankruptcy is less well understood. We estimated the incidence and relative risk of bankruptcy for people age twenty-one or older diagnosed with cancer compared to people the same age without cancer by conducting a retrospective cohort analysis that used a variety of medical, personal, legal, and bankruptcy sources covering the Western District of Washington State in US Bankruptcy Court for the period 1995-2009. We found that cancer patients were 2.65 times more likely to go bankrupt than people without cancer. Younger cancer patients had 2-5 times higher rates of bankruptcy than cancer patients age sixty-five or older, which indicates that Medicare and Social Security may mitigate bankruptcy risk for the older group. The findings suggest that employers and governments may have a policy role to play in creating programs and incentives that could help people cover expenses in the first year following a cancer diagnosis.

Abstract A tentative method for the rapid calculation of the pressure drop during forced-circulation boiling of water is presented. The method is based upon the application of pressure-drop data, obtained during the isothermal flow of air and various liquids, to the evaluation of local pressure gradients during forced-circulation boiling. Curves are developed by means of which the pressure drop during boiling can be estimated quickly once the exit quality, the boiling pressure, and the pressure drop for 100 per cent liquid are known. The proposed method is definitely an extrapolation of existing data and, as such, requires further experimental verification.

A photographic study was made of saturated nucleate pool boiling at a pressure of one atmosphere. Over 1000 still photographs and 12 high-speed motion pictures were taken of water boiling from a 2-in-dia flat horizontal surface facing upward. Two surfaces were studied, a 2/0 polished platinum surface and a 4/0 polished copper surface. The platinum surface was studied in the heat flux range of 14,700 to 176,000 Btu/hr, sq ft, and the copper surface from the incipient boiling heat flux of 10,500 Btu/hr, sq ft to the maximum flux of 493,000 Btu/hr, sq ft. Data were obtained for the breakoff diameters of discrete bubbles, and for the populations of active sites at heat fluxes up to 58,600 Btu/hr, sq ft. At least three, and possibly four, heat-transfer regions were found to exist in nucleate boiling, depending upon the mode of vapor generation. The vapor structures on the surface progressed through a sequence of first discrete bubbles, then vapor columns and vapor mushrooms, and finally vapor patches, as the surface temperature was increased. These individual vapor structures, or combinations of them, determine the mechanism of heat transfer in the four nucleate boiling regions. It was concluded that any heat-transfer model or design equation which is based on the dynamics of individual bubbles, or on any other single mechanism, must be in serious error.

A theoretical model is developed for predicting the maximum flow rate of a single component, two-phase mixture. It is based upon annular flow, uniform linear velocities of each phase, and equilibrium between liquid and vapor. Flow rate is maximized with respect to local slip ratio and static pressure for known stagnation conditions. Graphs are presented giving maximum steam/water flow rates for: local static pressures between 25 and 3,000 psia, with local qualities from 0.01 to 1.00; local stagnation pressures and enthalpies which cover the range of saturation states.

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCombinatorial and High-Throughput Development of Sensing Materials: The First 10 YearsRadislav A. Potyrailo and Vladimir M. MirskyView Author Information Chemical and Biological Sensing Laboratory, Materials Analysis and Chemical Sciences, General Electric Global Research, Niskayuna, New York 12309, and Institute of Analytical Chemistry, Chemo- and Biosensors, University of Regensburg, 93040 Regensburg, Germany Cite this: Chem. Rev. 2008, 108, 2, 770–813Publication Date (Web):January 23, 2008Publication History Received30 July 2007Published online23 January 2008Published inissue 1 February 2008https://doi.org/10.1021/cr068127fCopyright © 2008 American Chemical SocietyRequest reuse permissionsArticle Views7452Altmetric-Citations219LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (4 MB) Get e-AlertscloseSUBJECTS:Drug discovery,Materials,Polymers,Screening assays,Sensors Get e-Alerts

Abstract From the well-known Hertz theory of contact stresses, where contact is over a finite area, the more elementary two-dimensional case of contact between two cylinders with parallel generators may be obtained as a limiting case by allowing the contact area to become infinitely long in one direction. However, it is easier to obtain it directly; this is done in the paper.

Overdiagnosis of Parkinson's disease (PD) is suggested by specialist review of community diagnosis, and in postmortem studies. In specialist centers 4 to 15% of patients entered into clinical trials as early PD do not have functional imaging support for a PD diagnosis. In a European multicenter, prospective, longitudinal study, we compared clinical diagnosis with functional SPECT imaging using [123I]FP-CIT (DaTSCAN, GE Healthcare). Repeat observations were performed over 3 years in patients with tremor and/or parkinsonism in whom there was initial diagnostic uncertainty between degenerative parkinsonism and nondegenerative tremor disorders. Video-recording of clinical features was scored independently of functional imaging results by two blinded clinicians at 36 months (= gold standard clinical diagnosis). Three readers, unaware of the clinical diagnosis, classified the images as normal or abnormal by visual inspection. The main endpoint was the sensitivity and specificity of SPECT imaging at baseline compared with the gold standard. In 99 patients completing the three serial assessments, on-site clinical diagnosis overdiagnosed degenerative parkinsonism at baseline in diagnostically uncertain cases compared with the gold standard clinical diagnosis (at 36 months), the latter giving a sensitivity of 93% and specificity of 46%. The corresponding baseline [123I]FP-CIT SPECT results showed a mean sensitivity of 78% and a specificity of 97%. Inter-reader agreement for rating scans as normal or abnormal was high (Cohen's kappa = 0.94-0.97).

With the increasing age of the primary equipment of the electrical grids there exists also an increasing need to know its internal condition. For this purpose, off- and online diagnostic methods and systems for power transformers have been developed in recent years. Online monitoring is used continuously during operation and offers possibilities to record the relevant stresses which can affect the lifetime. The evaluation of these data offers the possibility of detecting oncoming faults early. In comparison to this, offline methods require disconnecting the transformer from the electrical grid and are used during planned inspections or when the transformer is already failure suspicious. This contribution presents the status and current trends of different diagnostic techniques of power transformers. It provides significant tutorial elements, backed up by case studies, results and some analysis. The broadness and improvements of the presented diagnostic techniques show that the power transformer is not anymore a black box that does not allow a view into its internal condition. Reliable and accurate condition assessment is possible leading to more efficient maintenance strategies.

Hyperpolarized 13C Magnetic Resonance Imaging (13C-MRI) provides a highly sensitive tool to probe tissue metabolism in vivo and has recently been translated into clinical studies. We report the cerebral metabolism of intravenously injected hyperpolarized [1–13C]pyruvate in the brain of healthy human volunteers for the first time. Dynamic acquisition of 13C images demonstrated 13C-labeling of both lactate and bicarbonate, catalyzed by cytosolic lactate dehydrogenase and mitochondrial pyruvate dehydrogenase respectively. This demonstrates that both enzymes can be probed in vivo in the presence of an intact blood-brain barrier: the measured apparent exchange rate constant (kPL) for exchange of the hyperpolarized 13C label between [1–13C]pyruvate and the endogenous lactate pool was 0.012 ± 0.006 s−1 and the apparent rate constant (kPB) for the irreversible flux of [1–13C]pyruvate to [13C]bicarbonate was 0.002 ± 0.002 s−1. Imaging also revealed that [1–13C]pyruvate, [1–13C]lactate and [13C]bicarbonate were significantly higher in gray matter compared to white matter. Imaging normal brain metabolism with hyperpolarized [1–13C]pyruvate and subsequent quantification, have important implications for interpreting pathological cerebral metabolism in future studies.

Intergranular stress corrosion cracking (SCC) of Inconel 600 is of concern to the nuclear power industry. Heat exchangers in commercial nuclear systems have shown SCC in only a fraction of a percent of the tubes in high temperature water, but laboratory SCC of Ni-containing alloys have been demonstrated by several research groups. This review revolves around French data, which show a reversal of the usual sensitizing effect in the case of SCC in high temperature, deaerated water. There is no cracking reported in material first heated so as to precipitate carbides at the grain boundaries, whereas high temperature annealed conditions lead to intergranular SCC in the same laboratory experiments. Electrochemically, SCC and also grain boundary corrosion are related to the potential level of a given test; however, it is not yet understood how the different grain boundary zones in Inconel 600 corrode (with and without applied stress) so that the mechanism of cracking remains speculative. Cr-depletion is sufficient to explain only some cases of intergranular corrosion. Grain boundary segregation seems to be of equal or greater importance in high temperature water, especially when the attack involves SCC. Grain boundaries may become cleaned when segregated elements dissolve in chromium carbide precipitates. Physically, precipitates at grain boundaries could possibly influence the manner in which the metal undergoes strain. Hydrogen as a cause of SCC has not been ruled out. The relationship between surface films formed and SCC of Alloy 600 in high temperature aqueous environments requires more work.

Wide deployment of wireless sensor and actuator networks in cyber-physical systems requires systematic design tools to enable dynamic tradeoff of network resources and control performance. In this paper, we consider three recently proposed aperiodic control algorithms which have the potential to address this problem. By showing how these controllers can be implemented over the IEEE 802.15.4 standard, a practical wireless control system architecture with guaranteed closed-loop performance is detailed. Event-based predictive and hybrid sensor and actuator communication schemes are compared with respect to their capabilities and implementation complexity. A two double-tank laboratory experimental setup, mimicking some typical industrial process control loops, is used to demonstrate the applicability of the proposed approach. Experimental results show how the sensor communication adapts to the changing demands of the control loops and the network resources, allowing for lower energy consumption and efficient bandwidth utilization.

The satisfactory prediction of the vapor volume fraction in subcooled boiling depends in large part on the ability to predict the point where a significant amount of net vapor is first formed. A method for the prediction of this point is derived here and compared with experimental measurements at both low and high fluid velocities. The derived relationships for this point include the effect of fluid properties, geometry, and the liquid velocity. A comparison with the empirical formula of Bowring [2] for water is given.

Copper(I)-based catalysts, such as Cu2S, are considered to be very promising materials for photocatalytic CO2 reduction. A common synthesis route for Cu2S via cation exchange from CdS nanocrystals requires Cu(I) precursors, organic solvents, and neutral atmosphere, but these conditions are not compatible with in situ applications in photocatalysis. Here we propose a novel cation exchange reaction that takes advantage of the reducing potential of photoexcited electrons in the conduction band of CdS and proceeds with Cu(II) precursors in an aqueous environment and under aerobic conditions. We show that the synthesized Cu2S photocatalyst can be efficiently used for the reduction of CO2 to carbon monoxide and methane, achieving formation rates of 3.02 and 0.13 μmol h(-1) g(-1), respectively, and suppressing competing water reduction. The process opens new pathways for the preparation of new efficient photocatalysts from readily available nanostructured templates.

Aircraft engines emit particulate matter (PM) that affects the air quality in the vicinity of airports and contributes to climate change. Nonvolatile PM (nvPM) emissions from aircraft turbine engines depend on fuel aromatic content, which varies globally by several percent. It is uncertain how this variability will affect future nvPM emission regulations and emission inventories. Here, we present black carbon (BC) mass and nvPM number emission indices (EIs) as a function of fuel aromatic content and thrust for an in-production aircraft gas turbine engine. The aromatics content was varied from 17.8% (v/v) in the neat fuel (Jet A-1) to up to 23.6% (v/v) by injecting two aromatic solvents into the engine fuel supply line. Fuel normalized BC mass and nvPM number EIs increased by up to 60% with increasing fuel aromatics content and decreasing engine thrust. The EIs also increased when fuel naphthalenes were changed from 0.78% (v/v) to 1.18% (v/v) while keeping the total aromatics constant. The EIs correlated best with fuel hydrogen mass content, leading to a simple model that could be used for correcting fuel effects in emission inventories and in future aircraft engine nvPM emission standards.

The free, nonlinear, fundamental period of transverse oscillation of axially moving strips (e.g., tapes, fibers, belts, and band saws) is determined by the approximate solution of two, coupled, nonlinear, partial differential equations. One equation describes longitudinal motion and the other transverse motion. A solution method is developed that permits accurate and efficient period calculations. The results indicate that the existence of the axial transport velocity reduces the fundamental period of oscillation and increases the relative importance of the nonlinear terms in the equations of motion. In many cases of practical interest the linear analysis is shown to be seriously in error and one may be led to erroneous conclusions because of its limited range of applicability. Curves are presented that assist one to estimate the accuracy of the linear period calculation.

Electron microscopy has been employed to investigate the structures of various face-centered cubic solid solutions, particularly austenitic alloys, which are susceptible and nonsusceptible to transgranular stress corrosion cracking. It has been found that susceptibility is associated with those alloys in which dislocations move in coplanar groups with little or no cross-slip either as a result of low stacking fault energy and/or short-range order. It is proposed that destruction of strong short-range order by plastic deformation in the slip planes is responsible for localized chemical attack and transgranular failure during stress corrosion. Co-planar groups of dislocations alone may not be responsible for the phenomenon; for example, Nichrome does not crack even though dislocations exist in coplanar arrays due to its low stacking fault energy. The model also predicts the change from intercrystalline to transcrystalline embrittlement observed in α-brass and the lack of susceptibility in random solid solutions. In pure metals and alloys where easy cross-slip and dislocation tangling occurs no transgranular susceptibility is found. Results are given for stacking fault energies, γ, in numerous austenitic alloys. It is further shown that certain alloying additions, e.g., Cr, Nb, and Ti in solid solution, appreciably decrease γ so that dislocations are always coplanar. Nitrogen does not appear to change γ but is also responsible for promoting coplanar dislocation arrays probably by increasing tendency for short-range order.

It is shown that the application of Schwarz's and Cauchy's Inequalities to the formulas for calculating Fhkl from, respectively, the density of scattering matter and the atomic positions in a crystal leads to relations between the magnitudes of some Fhkl's and the signs or phases of others. These relations are in the form of inequalities, which vary with the symmetry of the crystal under consideration. A table of the simplest inequalities applicable to crystals possessing each of the simple symmetry elements is included. Examples of the inequalities arising from the presence of combinations of symmetry elements are presented.