Hinckley and District Hospital

Formulated products contain some components that need to be replaced because of identified or suspected negative effects on health or the environment.

Abstract Background Vaccines against SARS-CoV-2 are still urgently needed as only 5% of the global population has been vaccinated. Here we report the safety and immunogenicity of a DNA vaccine (INO-4800) targeting the full-length Spike antigen of SARS-CoV-2 when given to adults at high-risk of exposure. Methods INO-4800 was evaluated in 401 participants randomized at a 3:3:1:1 ratio to receive either INO-4800 (1 mg or 2 mg dose) or placebo (1 or 2 injections) intradermally (ID) followed by electroporation (EP) using CELLECTRA® 2000 at Days 0 and 28. ClinicalTrials.gov Identifier: NCT04642638 Findings The majority of adverse events (AEs) were of Grade 1 and 2 in severity and did not appear to increase in frequency with the second dose. The number of participants experiencing each of the most common AEs did not differ appreciably between the two dosing groups. The geometric mean fold rise (GMFR) of binding and neutralizing antibody levels were statistically significantly greater in the 2.0 mg dose group versus the 1.0 mg dose group. The T cell immune responses measured by the ELISpot assay were also higher in the 2.0 mg dose group compared to the 1.0 mg dose group. Interpretation INO-4800 at both the 1.0 mg and 2.0 mg doses when administered in a 2-dose regimen appeared to be safe and well-tolerated in all adult ages. However, the comparative immunogenicity analysis favored selection of INO-4800 2.0 mg dose for advancement into a Phase 3 efficacy evaluation. Funding The trial was funded by the Department of Defense Joint Program Executive Office for Chemical, Biological, Radiological and Nuclear Defense, (JPEO-CBRND) in coordination with the Office of the Assistant Secretary of Defense for Health Affairs (OASD(HA)) and the Defense Health Agency. Research in context INO-4800 is among several vaccines being tested against SARS-CoV-2, the virus that causes COVID-19 with the goal of inducing a protective immune response. The DNA vaccine, INO-4800, administered by ID injection followed by electroporation (EP) using the CELLECTRA ® 2000 device, induces a balanced immune response that includes engagement of both T cells and B 1-5 . Added value of this study This is the first report of a randomized, blinded, placebo-controlled clinical trial of INO-4800, a DNA vaccine targeting the SARS-CoV-2 Spike antigen delivered ID followed by EP, in adults at high risk of SARS-CoV-2 exposure.

Background There are no fully oral recommended treatment regimens for gonorrhea. Inadequately treated pharyngeal gonococcal infections are a likely reservoir for transmission and development of antimicrobial resistance. We sought to determine an oral cefixime dosing regimen that would theoretically treat pharyngeal infections by gonococci with minimum inhibitory concentrations 0.5 μg/mL. Methods We conducted an open-label, nonrandomized, phase I pharmacokinetic and safety study of cefixime in 25 healthy male and female volunteers divided into 4 dosing cohorts (cohort A, 400 mg; cohort B, 800 mg; cohort C, 1200 mg; and cohort D, 800 mg every 8 hours × 3 doses [total dose 2400 mg]) with a target serum concentration of at least 2.0 μg/mL for more than 20 hours. Cefixime concentrations from serum and pharyngeal fluid were determined with use of a validated liquid chromatography–tandem mass spectrometry assay. Safety measures included laboratories, physical examinations, and symptom diaries. Results None of the single-dose regimens attained the target concentration; however, 50% of subjects in cohort D attained the target concentration. Variation in absorption and protein binding contributed to differences in concentrations. Pharyngeal fluid concentrations were negligible. The single-dose regimens were well tolerated; the multidose regimen resulted in mild to moderate gastrointestinal symptoms in 43% of subjects. Conclusions None of the dosing regimens achieved the target concentration. However, the proposed theoretical target was extrapolated from penicillin data; there are no empirically derived pharmacokinetic/pharmacodynamic criteria for pharyngeal gonorrhea. Under alternative cephalosporin-specific therapeutic goals, the multidose regimen may be effective, although the absence of cefixime in pharyngeal fluid is concerning. A clinical trial evaluating efficacy and defining pharmacokinetic/pharmacodynamic outcomes may be warranted.

Transcranial direct current stimulation (tDCS) has shown therapeutic potential to mitigate symptoms of various neurological disorders. Studies from our group and others used rodent models to demonstrate that tDCS modulates synaptic plasticity. We previously showed that 30 min of 0.25 mA tDCS administered to rats induced significant enhancement in the synaptic plasticity of hippocampal neurons. It has also been shown that tDCS induces expression of proteins known to mediate synaptic plasticity. This increase in synaptic plasticity may underly the observed therapeutic benefits of tDCS. However, the anti-inflammatory benefits of tDCS have not been thoroughly elucidated. Here we report that three sessions of tDCS spaced 1-3 weeks apart can significantly reduce levels of several inflammatory cytokines in brains of healthy rats. Rats receiving tDCS experienced enhanced synaptic plasticity without detectable improvement in behavioral tests or significant changes in astrocyte activation. The tDCS-mediated reduction in inflammatory cytokine levels supports the potential use of tDCS as a countermeasure against inflammation and offers additional support for the hypothesis that cytokines contribute to the modulation of synaptic plasticity.

Background: The pulmonary vasculature is essential for gas exchange and impacts both pulmonary and cardiac function. However, it is difficult to assess and its characteristics in the general population are unknown. We measured pulmonary blood volume (PBV) noninvasively using contrast enhanced, dual-energy computed tomography to evaluate its relationship to age and symptoms among older adults in the community. Methods: The MESA (Multi-Ethnic Study of Atherosclerosis) is an ongoing community-based, multicenter cohort. All participants attending the most recent MESA exam were selected for contrast enhanced dual-energy computed tomography except those with estimated glomerular filtration rate <60 mL/min per 1.73 m 2 . PBV was calculated by material decomposition of dual-energy computed tomography images. Multivariable models included age, sex, race/ethnicity, education, height, weight, smoking status, pack-years, and scanner model. Results: The mean age of the 727 participants was 71 (range 59–94) years, and 55% were male. The race/ethnicity distribution was 41% White, 29% Black, 17% Hispanic, and 13% Asian. The mean±SD PBV in the youngest age quintile was 547±180 versus 433±194 mL in the oldest quintile ( P <0.001), with an approximately linear decrement of 50 mL per 10 years of age ([95% CI, 32–67]; P <0.001). Findings were similar with multivariable adjustment. Lower PBV was associated independently with a greater dyspnea after a 6-minute walk ( P =0.04) and greater composite dyspnea symptom scores ( P =0.02). Greater PBV was also associated with greater height, weight, lung volume, Hispanic race/ethnicity, and nonsmoking history. Conclusions: Pulmonary blood volume was substantially lower with advanced age and was associated independently with greater symptoms scores in the elderly.

Tick-borne diseases (TBDs) are increasing despite prevention recommendations. We explored whether cost is a barrier to prevention use in Connecticut and Maryland, using a cross-sectional survey. Respondents were queried regarding their willingness to pay for chemical, natural, and rodent-targeted yard pesticide treatments and permethrin-treated clothing. We evaluated associations between demographics, TBD knowledge and attitudes, and willingness to pay for prevention methods. Most respondents would pay for yard treatments (85%); 95% preferring natural pesticide, and 82% would pay for permethrin-treated clothing. Most did not want to pay more than $99 for any of the yard treatments. Having a household income of $100 000 was associated with willingness to pay $100 or more for chemical, natural, or rodent-targeted treatments and $25 or more for permethrin self-treated and pretreated clothing. Yard treatments, especially natural pesticides, were acceptable for TBD prevention; however, current pricing may be cost-prohibitive. Permethrin-treated clothing may be an affordable and acceptable prevention method.

Abstract We assessed population status and estimated selected demographic parameters for lake sturgeon Acipenser fulvescens in the Kettle River, Minnesota, using capture–recapture tagging data collected from 1992 to 2007. The lake sturgeon is an imperiled species of special concern in Minnesota, with population declines attributed to overfishing, pollution, and establishment of dams. In 1995, the recreational fishery was closed and the only dam on the Kettle River (Sandstone Dam) was removed, in part to promote lake sturgeon recovery. Recent incidental capture of lake sturgeon by anglers is prompting interest in re-opening the recreational fishery. We gathered information to determine (1) status and demography of the Kettle River population, (2) the effect of dam removal, and (3) the feasibility of re-opening the recreational fishery. Open-population capture–recapture models were used to examine population status and estimate survival, seniority, and the relative importance of survival and recruitment for influencing population trends. The rate of population change (λ) indicated that the population was barely maintaining itself (average λ across years = 1.02; 95% confidence interval [CI] = 0.86–1.16). Annual population estimates ranged from about 130 fish to almost 300 fish but had wide CIs. Similarly, estimates of new lake sturgeon entering the population each year (either from within-population recruitment or immigration) were variable and ranged from 0 to over 100. Annual survival was nearly constant at about 80%. Growth was slow relative to other populations but averaged about 28 mm/year for ages 6–21. A seniority parameter indicated that 49–87% of individuals in the population in a given year consisted of population members that survived from the previous year. This suggested that the population was essentially maintaining itself through a combination of episodic recruitment and relatively constant survival. Recent low recruitment may be due to a short-term disturbance from sediment released when the dam was removed in 1995. Maintaining closure of the recreational fishery still appears necessary. Bolstering of recruitment may be needed to increase the population. Full recovery will require patience for this long-lived, late-maturing, infrequently reproducing species.

Acne vulgaris, a chronic condition associated with overgrowth of Propionibacterium acnes and Staphylococcus epidermidis, is commonly treated with antibiotics. However, the emergence of antibiotic resistance has resulted in a need for alternative therapies. The aim of this study is to develop a topical preparation incorporating essential oils (EOs) for use against acne-associated bacteria and assess its efficacy against prescription therapies Dalacin T and Stiemycin. Antimicrobial screening of rosewood, clove bud and litsea EOs was conducted before interactions between binary and ternary combinations were determined against P. acnes and S. epidermidis (type and clinical isolates) using minimum inhibitory concentrations and fractional inhibitory concentrations. The EOs were characterised by both gas chromatography–mass spectrometry and nuclear magnetic resonance. A combination of 0.53 mg/mL litsea, 0.11 mg/mL rosewood and 0.11 mg/mL clove bud was formulated into herbal distillates and compared with Dalacin T and Stiemycin against antibiotic sensitive and resistant isolates (erythromycin). The distillate with EO had synergistic activity against P. acnes (7log10 reduction) and indifferent activity against S. epidermidis (6log10 reduction); antimicrobial activity was either significantly (p ≤ 0.05) more antimicrobial or equivalent to that of Dalacin T and Stiemycin. This formulation may serve as a valuable alternative for the control of acne vulgaris-associated bacteria. Copyright © 2017 John Wiley & Sons, Ltd.

BACKGROUND: Medicare payment has been examined in a variety of medical and surgical specialties. This study examines Medicare payment in the subspecialty of orthopaedic oncology. METHODS: The Physician Fee Schedule Look-up Tool was used to obtain payment information from 2000 to 2020 for procedures related to orthopaedic oncology billed to Medicare. RESULTS: For the 38 included orthopaedic oncology procedures, inflation-adjusted Medicare payment decreased an average of 13.6% overall from 2000 to 2020. After adjusting for inflation, the payment for procedures related to spine and pelvis increased by 7.6%, procedures relating to limb salvage increased by 14.6%, procedures associated with the surgical management of complications decreased by 26.9%, and procedures relating to metastatic disease management decreased by 34.8%. CONCLUSION: Medicare payment has declined by 13.6% from 2000 to 2020. This variation in Medicare payment represents a difference in valuation of these procedures by the Centers for Medicare and Medicaid Services and could be used to direct healthcare policy.

Abstract There is an urgent need to identify safe and effective combination treatments for multidrug‐resistant (MDR) Mycobacterium tuberculosis infection (TB). Bedaquiline, a new diarylquinoline, is approved for the treatment of MDR pulmonary TB in combination with other drugs, which could include rifabutin, which is also used to treat drug‐resistant TB. Both rifabutin and bedaquiline are metabolized via cytochrome P450 3A4, and rifabutin is an inducer of this enzyme. Bedaquiline is metabolized into its primary N ‐monodesmethyl metabolite, M2, and further desmethylated into an N‐ didesmethyl metabolite, M3. Both metabolites are cytotoxic and induce phospholipidosis. The effect of rifabutin on the generation and disposition of the 2 metabolites was investigated in healthy adult volunteers coadministered bedaquiline and either rifabutin or rifampin. Subjects received single oral doses (400 mg) of bedaquiline on days 1 and 29. Oral rifabutin (300 mg) or rifampin (600 mg) were given daily on days 20–41. In the rifabutin group maximum M2 concentrations (C max ) increased significantly ( P < .001) from 47.59 to 79.53 ng/mL, and clearance slowed slightly ( P = .01). This resulted in significantly ( P < .001) increased overall exposure (area under the concentration‐time curve [AUC 0‐τ ]). Peak concentrations of M3 increased approximately 3‐fold with little decline thereafter. In rifampin recipients M2 C max doubled (48.44 to 101.52 ng/mL), but M2 clearance and time to C max significantly ( P < .001) increased, and AUC 0‐∞ and mean residence time significantly decreased ( P < .001). Peak M3 concentrations increased 4‐fold and rapidly declined. Although both rifamycins accelerate desmethylation of bedaquiline and M2, differences in clearance resulted in sustained elevations of both metabolites during rifabutin, but not rifampin, treatment.

Abstract Slope failures are an ongoing global threat leading to significant numbers of fatalities and infrastructure damage. Landslide impact on communities can be reduced using efficient early warning systems to plan mitigation measures and protect elements at risk. This manuscript presents an innovative geophysical approach to monitoring landslide dynamics, which combines electrical resistivity tomography (ERT) and low-frequency distributed acoustic sensing (DAS), and was deployed on a slope representative of many landslides in clay rich lowland slopes. ERT is used to create detailed, dynamic moisture maps that highlight zones of moisture accumulation leading to slope instability. The link between ERT derived soil moisture and the subsequent initiation of slope deformation is confirmed by low-frequency DAS measurements, which were collocated with the ERT measurements and provide changes in strain at unprecedented spatiotemporal resolution. Auxiliary hydrological and slope displacement data support the geophysical interpretation. By revealing critical zones prone to failure, this combined ERT and DAS monitoring approach sheds new light on landslide mechanisms. This study demonstrates the advantage of including subsurface geophysical monitoring techniques to improve landslide early warning approaches, and highlights the importance of relying on observations from different sources to build effective landslide risk management strategies.

Ita Connection with the Past.

Suitably labeled Evans blue dye has been successfully applied to evaluate cardiac function, vascular permeability, and lymphatic imaging in preclinical settings. This study documented the first-in-human application of ⁶⁸Ga-1,4,7-triazacyclononane-<i>N,N′,N″-</i>triacetic acid (NOTA)-NEB. <b>Methods:</b> The NOTA-conjugated truncated form of Evans blue, NEB, was labeled with ⁶⁸Ga and tested in BALB/C mice for dynamic PET and ex vivo biodistribution studies. Three healthy volunteers (2 men and 1 woman) underwent 90-min whole-body dynamic PET. The absorbed doses for major organs and whole body were calculated using OLINDA/EXM software. Eleven patients with focal hepatic lesions diagnosed by enhanced CT or MR imaging were subjected to whole-body PET/CT acquisitions at 30 min after intravenous injection of 111–148 MBq (3–4 mCi) of ⁶⁸Ga-NEB. <b>Results:</b> NEB dye was labeled with ⁶⁸Ga (half-time, 68 min) with high yield and purity. After intravenous injection, ⁶⁸Ga-NEB formed a complex with serum albumin, thus most of the radioactivity was retained in blood circulation. The tracer was demonstrated to be safe in both healthy volunteers and recruited patients without side effects or allergies. Among the 11 patients, hemangiomas showed much higher ⁶⁸Ga-NEB signal intensity than the surrounding normal hepatic tissues, whereas no apparent difference between lesions and hepatic tissues was identified on ¹⁸F-FDG PET. All other focal hepatic lesions including hepatocellular carcinoma, hepatic cysts, and neuroendocrine tumor liver metastases showed negative ⁶⁸Ga-NEB contrast to hepatic tissues. <b>Conclusion:</b> As a blood-pool imaging agent, ⁶⁸Ga-NEB is safe to use in the clinic, and our preliminary studies demonstrate the value of differentiating hepatic hemangioma from other benign or malignant focal hepatic lesions. Easy labeling with different positron emitters of various half-lives, excellent pharmacokinetics, and imaging quality warrant further clinical applications of NEB-based PET tracers.

CONTEXT: In the northeastern United States, recommendations to prevent diseases spread by black-legged ticks ( Ixodes scapularis ) and lone star ticks ( Amblyomma americanum ) often rely on individuals to use personal protection or yard-based strategies. The 4-Poster deer treatment stations (4-Posters) suppress tick populations by treating deer hosts with acaricide, potentially offering a community-wide approach for reducing tick-borne diseases in endemic areas. The 4-Poster deployment logistics in mainland community settings are not well documented but are needed for future public health tick control efforts. PROGRAM: As part of a public health research effort to design a population-based 4-Poster effectiveness study aimed at reducing tick-borne disease incidence, TickNET researchers partnered with the Town of Ridgefield (Connecticut) to understand the feasibility and operational logistics of deploying 4-Posters on public land within a residential community to inform future public health interventions by municipalities or vector control agencies. IMPLEMENTATION: We deployed three 4-Posters on a municipal property from July to December 2020 and used motion-activated cameras to record wildlife activity nearby. We documented per-device operational details, costs, materials consumed, and animal activity. EVALUATION: Operation of 4-Posters was feasible, and device challenges were easily remedied. Deer visitation and heavy nontarget animal use were documented at all devices. Unexpectedly, monthly corn consumption was not correlated with monthly deer-view days. The monthly cost per device was US $1279 or US $305 per hectare with an average 21 minutes of weekly service time. DISCUSSION: Use of 4-Posters by communities, public health agencies, or vector control programs may be a practicable addition to tick management programs in tick-borne disease endemic areas in the Northeast. Such programs should carefully consider local and state regulations, follow manufacturer and pesticide label guidelines, and include wildlife monitoring. High labor costs incurred in this project could be mitigated by training vector control agency or municipality staff to service 4-Posters.

The structure of some past and present rules is discussed and the general problem of optimum performance under the rule is considered. This requires a rational performance model, which would itself form the most equitable rating rule possible under the existing level of technical understanding of mechanics of sailing. The theory of sailboat performance estimates is outlined and surveyed. New theories are presented on the performances of geometrically similar vessels and on the implications of optimum sail trim. Two rational ways are proposed for averaging performance over a probability distribution of operating conditions appropriate to different types of races. The theory suggests a new form for a rule, in which multiple ratings are assigned characterizing average potential speeds in various ranges of operating conditions.

A discussion is presented on the organization and operation of the Partnership for America's Cup Technology (PACT). Founded in February 1990 when individual American syndicates were unable to fund productive research and design programs, PACT's mission was to help the U.S. America's Cup Defense overcome the technical lead held by several foreign challengers in the new International America's Cup Class (IACC). PACT was to conduct cooperative technology development projects relevant to IACC yacht design to support all U.S. syndicates competing to defend the America's Cup. PACT had four major programs: gathering site specific environmental data; testing parametric series of hulls or appendages with associated improvements in testing methods; developing Computational Fluid Dynamics tools benchmarked by suitable experiments; developing and maintaining VPP centered design evaluation software. Since PACT was not involved in design itself, American syndicates maintained their own proprietary high level design programs. In areas where syndicates did not have comparable research programs, PACTs work was integrated into the syndicate design process and often played a role in their final designs. When PACT programs overlapped existing syndicate research, PACT provided a valuable second opinion. Planning and conducting PACT research was a team effort involving syndicate representatives and independent researchers. Regularly scheduled meetings and formal reports were used to distribute information to the American Syndicates.

During court hearings arising from traffic accidents, videotaped recordings are often used to give a ‘drive through’ view of the accident scene. A panel of 24 subjects evaluated the impression of speed created by such recordings. Focal length of the camera lens has a marked effect.

Health promotion activities with children and young people are important as they take messages about health seriously and can be influential in spreading messages about healthy living to their friends and families. Child health professionals have an important role to play in passing on messages of positive health to children and young people. Peer education is a useful way of passing on messages about health to young people. This article shares examples of three health promotion projects with children in a community trust, looking at asthma, sex education and testicular examination.

CONTEXT: Public health programs promote numerous tickborne disease (TBD) prevention measures. However, measures are not frequently or consistently performed. OBJECTIVE: Describe barriers to consistent use of 4 commonly promoted TBD prevention measures. DESIGN: We conducted an online survey (n = 1883) evaluating behaviors regarding TBD prevention measures including conducting tick checks, applying insect repellents, showering/bathing, and applying chemical or natural pesticides to residential yards. Respondents could select reasons for never, rarely, or sometimes performing these measures. Descriptive analysis and logistic regression modeling evaluated associations between the 3 most cited barriers for each measure and select demographic variables. SETTING: The survey was administered to residents in high Lyme disease incidence counties of Connecticut and Maryland, 2016-2017. RESULTS: For tick checks (n = 800), the most cited barriers were forgetting (63%), not spending time in tick habitat (28%), and too much trouble (11%). For applying insect repellents (n = 1303), the most cited barriers were forgetting (38%), personal safety concerns (24%), and too much trouble (19%). For showering/bathing 2 hours after outdoor activity in tick habitat (n = 1080), the most cited barriers were being unaware of the prevention measure (51%), too much trouble (18%), and forgetting (18%). For applying chemical pesticides to yards (n = 1320), the most cited barriers were having environmental (45%), pet safety (31%), and personal safety concerns (28%). Lastly, for applying natural pesticides to yards (n = 1357), the most cited barriers were being unaware of natural pesticides (31%), having cost concerns (23%), and not being concerned about ticks on property (16%). CONCLUSIONS: Forgetting, too much trouble, unawareness, and safety concerns were primary barriers to using several TBD prevention measures. Education regarding effectiveness, safety, and timing may increase uptake of certain measures. These challenges can be difficult to address, highlighting the need for passive TBD prevention measures, such as a Lyme disease vaccine.

PreviousNext You have accessSymposium on the Application of Geophysics to Engineering and Environmental Problems 2016Geophysics for Water ResourcesAuthors: Bradley CarrChris MoodyBern HinckleyDarren ParkinMark ZellmanJamey TurnerDaniel O'ConnellPaul SchweringPhil SirlesMargot TruiniMelvyn BestAdrian HickinAndre J. M. PuginAbe BanjiTimothy EadieAlexander PrikhodkoGeoffrey PlastowCarlos IzarraCarlos SalasBill BrownAaron DavisTimothy MundayRambhatla G. SastryKasporov BonthuBrent BarkerMatt SpurlinBrad CrossCraig DivineFardous ZarifLee SlaterMohamed A. MabroukAhmed M. A. YoussefAyman M. Al-TemamySalah A. MousaKaram S. I. FaragJudy RobinsonBradley CarrWyCEHG - University of Wyoming, Chris MoodyWyoming Groundwater, LLC., Bern HinckleyHinckley Consulting, Darren ParkinCity of Laramie Wyoming Dept. of Water Resources, Mark ZellmanFugro Consultants, Jamey TurnerFugro Consultants, Daniel O'ConnellFugro Consultants, Paul SchweringOlson Engineering, Phil SirlesOlson Engineering, Margot Truini, Melvyn BestBemex Consulting International, Adrian HickinBritish Columbia Geological Survey, British Columbia, Andre J. M. PuginGeological Survey of Canada, Abe BanjiNiomr, Lagos, Timothy EadieGeotech Ltd., Alexander PrikhodkoGeotech Ltd., Geoffrey PlastowGeotech Ltd., Carlos IzarraGeotech Ltd., Carlos SalasGeoscience BC, British Columbia, Bill BrownSkyTEM Canada, Ontario, Aaron DavisCSIRO, Timothy MundayCSIRO, Rambhatla G. SastryIndian Institute of Technology Roorkee, Kasporov BonthuIIT Roorkee, Brent BarkerARCADIS, Matt SpurlinARCADIS, Brad CrossArcadis, Craig DivineArcadis, Fardous ZarifGeophysical Exploration Department, Desert Research Center (DRC), Matarya, Cairo, Egypt, Lee SlaterDepartment of Earth & Environmental Sciences, Rutgers-Newark University, USA, Mohamed A. MabroukGeophysical Exploration Department, Desert Research Center (DRC), Matarya, Cairo, Egypt, Ahmed M. A. YoussefGeophysical Exploration Department, Desert Research Center (DRC), Matarya, Cairo, Egypt, Ayman M. Al-TemamyGeophysical Exploration Department, Desert Research Center (DRC), Matarya, Cairo, Egypt, Salah A. MousaGeophysics Department, Faculty of Science, Ain Shams University, Abbassia, Cairo, Egypt, Karam S. I. FaragGeophysics Department, Faculty of Science, Ain Shams University, Abbassia, Cairo, Egypt, and Judy RobinsonDepartment of Earth & Environmental Sciences, Rutgers-Newark University, USAhttps://doi.org/10.4133/SAGEEP.29-039 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail Abstract The individual abstracts for this session are available to read in the PDF. Keywords: Municipal Water, Fracture Permeability, Borehole geophysics, groundwater contamination, Cheraw, Teton, Fault, Characterization, IMASW, seismic, reflection, hydrogeology, extension, fractures, aquifer, electromagnetic, shallow, stratigraphy, lithology, Geo-electric layer, Schlumberger array, Wenner array, vertical electrical sounding and saltwater, HTEM, TAU, inversion, resistivity, AEM, airborne electromagnetics, survey planning, Murchison. groundwater, Time-lapse ERT, Time-lapse VES, 4-D aquifer monitoring, 4-D gravity aquifer monitoring, nuclear magnetic resonance, NMR, NAPL, light non-aqueous phase liquids, hydroca, fractured limestone, coastalPermalink: https://doi.org/10.4133/SAGEEP.29-039FiguresReferencesRelatedDetails Symposium on the Application of Geophysics to Engineering and Environmental Problems 2016ISSN (online):1554-8015Copyright: 2016 Pages: 647 publication data© 2016 Published in electronic format with permission by the Society of Exploration Geophysicists and Environment and Engineering Geophysical SocietyPublisher:Environmental & Engineering Geophysical Society HistoryPublished Online: 24 Mar 2016 CITATION INFORMATION Bradley Carr, Chris Moody, Bern Hinckley, Darren Parkin, Mark Zellman, Jamey Turner, Daniel O'Connell, Paul Schwering, Phil Sirles, Margot Truini, Melvyn Best, Adrian Hickin, Andre J. M. Pugin, Abe Banji, Timothy Eadie, Alexander Prikhodko, Geoffrey Plastow, Carlos Izarra, Carlos Salas, Bill Brown, Aaron Davis, Timothy Munday, Rambhatla G. Sastry, Kasporov Bonthu, Brent Barker, Matt Spurlin, Brad Cross, Craig Divine, Fardous Zarif, Lee Slater, Mohamed A. Mabrouk, Ahmed M. A. Youssef, Ayman M. Al-Temamy, Salah A. Mousa, Karam S. I. Farag, and Judy Robinson, (2016), "Geophysics for Water Resources," Symposium on the Application of Geophysics to Engineering and Environmental Problems Proceedings : 218-229. https://doi.org/10.4133/SAGEEP.29-039 Plain-Language Summary KeywordsMunicipal WaterFracture PermeabilityBorehole geophysicsgroundwater contaminationCherawTetonFaultCharacterizationIMASWseismicreflectionhydrogeologyextensionfracturesaquiferelectromagneticshallowstratigraphylithologyGeo-electric layerSchlumberger arrayWenner arrayvertical electrical sounding and saltwaterHTEMTAUinversionresistivityAEMairborne electromagneticssurvey planningMurchison. groundwaterTime-lapse ERTTime-lapse VES4-D aquifer monitoring4-D gravity aquifer monitoringnuclear magnetic resonanceNMRNAPLlight non-aqueous phase liquidshydrocafractured limestonecoastalPDF DownloadLoading ...