NobleBlocks

Institute of High Energy Physics

facilityBeijing, China

Research output, citation impact, and the most-cited recent papers from Institute of High Energy Physics (China). Aggregated across the NobleBlocks index of 300M+ scholarly works.

Total works
27.6K
Citations
10.0M
h-index
882
i10-index
155.3K
Also known as
Institute of High Energy Physics中国科学院高能物理研究所

Top-cited papers from Institute of High Energy Physics

The CMS experiment at the CERN LHC
S. Chatrchyan, G. Hmayakyan, V. Khachatryan, A. M. Sirunyan +4 more
2008· Journal of Instrumentation5.4Kdoi:10.1088/1748-0221/3/08/s08004

The Compact Muon Solenoid (CMS) detector is described. The detector operates at the Large Hadron Collider (LHC) at CERN. It was conceived to study proton-proton (and lead-lead) collisions at a centre-of-mass energy of 14 TeV (5.5 TeV nucleon-nucleon) and at luminosities up to 1034 cm−2 s−1 (1027 cm−2 s−1). At the core of the CMS detector sits a high-magnetic-field and large-bore superconducting solenoid surrounding an all-silicon pixel and strip tracker, a lead-tungstate scintillating-crystals electromagnetic calorimeter, and a brass-scintillator sampling hadron calorimeter. The iron yoke of the flux-return is instrumented with four stations of muon detectors covering most of the 4π solid angle. Forward sampling calorimeters extend the pseudorapidity coverage to high values (|η| ≤ 5) assuring very good hermeticity. The overall dimensions of the CMS detector are a length of 21.6 m, a diameter of 14.6 m and a total weight of 12500 t.

Review of Particle Physics
Particle Data Group, P. Żyła, R.M. Barnett, J. Beringer +4 more
2020· Progress of Theoretical and Experimental Physics5.2Kdoi:10.1093/ptep/ptaa104

Abstract The Review summarizes much of particle physics and cosmology. Using data from previous editions, plus 3,324 new measurements from 878 papers, we list, evaluate, and average measured properties of gauge bosons and the recently discovered Higgs boson, leptons, quarks, mesons, and baryons. We summarize searches for hypothetical particles such as supersymmetric particles, heavy bosons, axions, dark photons, etc. Particle properties and search limits are listed in Summary Tables. We give numerous tables, figures, formulae, and reviews of topics such as Higgs Boson Physics, Supersymmetry, Grand Unified Theories, Neutrino Mixing, Dark Energy, Dark Matter, Cosmology, Particle Detectors, Colliders, Probability and Statistics. Among the 120 reviews are many that are new or heavily revised, including a new review on High Energy Soft QCD and Diffraction and one on the Determination of CKM Angles from B Hadrons. The Review is divided into two volumes. Volume 1 includes the Summary Tables and 98 review articles. Volume 2 consists of the Particle Listings and contains also 22 reviews that address specific aspects of the data presented in the Listings. The complete Review (both volumes) is published online on the website of the Particle Data Group (pdg.lbl.gov) and in a journal. Volume 1 is available in print as the PDG Book. A Particle Physics Booklet with the Summary Tables and essential tables, figures, and equations from selected review articles is available in print and as a web version optimized for use on phones as well as an Android app.

Review of Particle Physics
S. Navas, C. Amsler, Th. Gutsche, C. Hanhart +4 more
2024· Physical review. D/Physical review. D.2.8Kdoi:10.1103/physrevd.110.030001

The summarizes much of particle physics and cosmology. Using data from previous editions, plus 2,717 new measurements from 869 papers, we list, evaluate, and average measured properties of gauge bosons and the recently discovered Higgs boson, leptons, quarks, mesons, and baryons. We summarize searches for hypothetical particles such as supersymmetric particles, heavy bosons, axions, dark photons, etc. Particle properties and search limits are listed in Summary Tables. We give numerous tables, figures, formulae, and reviews of topics such as Higgs Boson Physics, Supersymmetry, Grand Unified Theories, Neutrino Mixing, Dark Energy, Dark Matter, Cosmology, Particle Detectors, Colliders, Probability and Statistics. Most of the 120 reviews are updated, including many that are heavily revised. The is divided into two volumes. Volume 1 includes the Summary Tables and 97 review articles. Volume 2 consists of the Particle Listings and contains also 23 reviews that address specific aspects of the data presented in the Listings. The complete (both volumes) is published online on the website of the Particle Data Group () and in a journal. Volume 1 is available in print as the . A with the Summary Tables and essential tables, figures, and equations from selected review articles is available in print, as a web version optimized for use on phones, and as an Android app. The 2024 edition of the Review of Particle Physics should be cited as: S. Navas et al. (Particle Data Group), Phys. Rev. D 110, 030001 (2024) © 2024 2024

First Results from KamLAND: Evidence for Reactor Antineutrino Disappearance
K. Eguchi, S. Enomoto, K. Furuno, J. Goldman +4 more
2003· Physical Review Letters2.7Kdoi:10.1103/physrevlett.90.021802

KamLAND has measured the flux of ${\overline{\ensuremath{\nu}}}_{e}$'s from distant nuclear reactors. We find fewer ${\overline{\ensuremath{\nu}}}_{e}$ events than expected from standard assumptions about ${\overline{\ensuremath{\nu}}}_{e}$ propagation at the 99.95% C.L. In a $162\text{ }\mathrm{\text{ton}}\ifmmode\cdot\else\textperiodcentered\fi{}\mathrm{y}\mathrm{r}$ exposure the ratio of the observed inverse $\ensuremath{\beta}$-decay events to the expected number without ${\overline{\ensuremath{\nu}}}_{e}$ disappearance is $0.611\ifmmode\pm\else\textpm\fi{}0.085\mathrm{(}\mathrm{s}\mathrm{t}\mathrm{a}\mathrm{t}\mathrm{)}\ifmmode\pm\else\textpm\fi{}0.041\mathrm{(}\mathrm{s}\mathrm{y}\mathrm{s}\mathrm{t}\mathrm{)}$ for ${\overline{\ensuremath{\nu}}}_{e}$ energies $>3.4\text{ }\text{ }\mathrm{M}\mathrm{e}\mathrm{V}$. In the context of two-flavor neutrino oscillations with CPT invariance, all solutions to the solar neutrino problem except for the ``large mixing angle'' region are excluded.

Homogeneously dispersed multimetal oxygen-evolving catalysts
Bo Zhang, X. R. Zheng, Oleksandr Voznyy, Riccardo Comin +4 more
2016· Science2.4Kdoi:10.1126/science.aaf1525

Earth-abundant first-row (3d) transition metal-based catalysts have been developed for the oxygen-evolution reaction (OER); however, they operate at overpotentials substantially above thermodynamic requirements. Density functional theory suggested that non-3d high-valency metals such as tungsten can modulate 3d metal oxides, providing near-optimal adsorption energies for OER intermediates. We developed a room-temperature synthesis to produce gelled oxyhydroxides materials with an atomically homogeneous metal distribution. These gelled FeCoW oxyhydroxides exhibit the lowest overpotential (191 millivolts) reported at 10 milliamperes per square centimeter in alkaline electrolyte. The catalyst shows no evidence of degradation after more than 500 hours of operation. X-ray absorption and computational studies reveal a synergistic interplay between tungsten, iron, and cobalt in producing a favorable local coordination environment and electronic structure that enhance the energetics for OER.

Single Cobalt Atoms with Precise N‐Coordination as Superior Oxygen Reduction Reaction Catalysts
Peiqun Yin, Tao Yao, Yuen Wu, Lirong Zheng +4 more
2016· Angewandte Chemie International Edition2.2Kdoi:10.1002/anie.201604802

A new strategy for achieving stable Co single atoms (SAs) on nitrogen-doped porous carbon with high metal loading over 4 wt % is reported. The strategy is based on a pyrolysis process of predesigned bimetallic Zn/Co metal-organic frameworks, during which Co can be reduced by carbonization of the organic linker and Zn is selectively evaporated away at high temperatures above 800 °C. The spherical aberration correction electron microscopy and extended X-ray absorption fine structure measurements both confirm the atomic dispersion of Co atoms stabilized by as-generated N-doped porous carbon. Surprisingly, the obtained Co-Nx single sites exhibit superior ORR performance with a half-wave potential (0.881 V) that is more positive than commercial Pt/C (0.811 V) and most reported non-precious metal catalysts. Durability tests revealed that the Co single atoms exhibit outstanding chemical stability during electrocatalysis and thermal stability that resists sintering at 900 °C. Our findings open up a new routine for general and practical synthesis of a variety of materials bearing single atoms, which could facilitate new discoveries at the atomic scale in condensed materials.

Observation of Electron-Antineutrino Disappearance at Daya Bay
Fengpeng An, J. Z. Bai, A. B. Balantekin, H. R. Band +4 more
2012· Physical Review Letters2.2Kdoi:10.1103/physrevlett.108.171803

The Daya Bay Reactor Neutrino Experiment has measured a nonzero value for the neutrino mixing angle ${\ensuremath{\theta}}_{13}$ with a significance of 5.2 standard deviations. Antineutrinos from six 2.9 $\mathrm{G}{\mathrm{W}}_{\mathrm{th}}$ reactors were detected in six antineutrino detectors deployed in two near (flux-weighted baseline 470 m and 576 m) and one far (1648 m) underground experimental halls. With a $43\text{ }000\text{ }\text{ }\mathrm{ton}--\mathrm{G}{\mathrm{W}}_{\mathrm{th}}--\mathrm{day}$ live-time exposure in 55 days, 10 416 (80 376) electron-antineutrino candidates were detected at the far hall (near halls). The ratio of the observed to expected number of antineutrinos at the far hall is $R=0.940\ifmmode\pm\else\textpm\fi{}\phantom{\rule{0ex}{0ex}}0.011(\mathrm{stat}.)\ifmmode\pm\else\textpm\fi{}0.004(\mathrm{syst}.)$. A rate-only analysis finds ${sin}^{2}2{\ensuremath{\theta}}_{13}=0.092\ifmmode\pm\else\textpm\fi{}0.016(\mathrm{stat}.)\ifmmode\pm\else\textpm\fi{}0.005(\mathrm{syst}.)$ in a three-neutrino framework.

Isolated Single Iron Atoms Anchored on N‐Doped Porous Carbon as an Efficient Electrocatalyst for the Oxygen Reduction Reaction
Yuanjun Chen, Shufang Ji, Yang‐Gang Wang, Juncai Dong +4 more
2017· Angewandte Chemie International Edition2.0Kdoi:10.1002/anie.201702473

Abstract The development of low‐cost, efficient, and stable electrocatalysts for the oxygen reduction reaction (ORR) is desirable but remains a great challenge. Herein, we made a highly reactive and stable isolated single‐atom Fe/N‐doped porous carbon (ISA Fe/CN) catalyst with Fe loading up to 2.16 wt %. The catalyst showed excellent ORR performance with a half‐wave potential ( E 1/2 ) of 0.900 V, which outperformed commercial Pt/C and most non‐precious‐metal catalysts reported to date. Besides exceptionally high kinetic current density ( J k ) of 37.83 mV cm −2 at 0.85 V, it also had a good methanol tolerance and outstanding stability. Experiments demonstrated that maintaining the Fe as isolated atoms and incorporating nitrogen was essential to deliver the high performance. First principle calculations further attributed the high reactivity to the high efficiency of the single Fe atoms in transporting electrons to the adsorbed OH species.

First M87 Event Horizon Telescope Results. VI. The Shadow and Mass of the Central Black Hole
Kazunori Akiyama, A. Alberdi, W. Alef, Keiichi Asada +4 more
2019· The Astrophysical Journal Letters1.6Kdoi:10.3847/2041-8213/ab1141

Abstract We present measurements of the properties of the central radio source in M87 using Event Horizon Telescope data obtained during the 2017 campaign. We develop and fit geometric crescent models (asymmetric rings with interior brightness depressions) using two independent sampling algorithms that consider distinct representations of the visibility data. We show that the crescent family of models is statistically preferred over other comparably complex geometric models that we explore. We calibrate the geometric model parameters using general relativistic magnetohydrodynamic (GRMHD) models of the emission region and estimate physical properties of the source. We further fit images generated from GRMHD models directly to the data. We compare the derived emission region and black hole parameters from these analyses with those recovered from reconstructed images. There is a remarkable consistency among all methods and data sets. We find that >50% of the total flux at arcsecond scales comes from near the horizon, and that the emission is dramatically suppressed interior to this region by a factor >10, providing direct evidence of the predicted shadow of a black hole. Across all methods, we measure a crescent diameter of 42 ± 3 μ as and constrain its fractional width to be <0.5. Associating the crescent feature with the emission surrounding the black hole shadow, we infer an angular gravitational radius of GM / Dc 2 = 3.8 ± 0.4 μ as. Folding in a distance measurement of gives a black hole mass of . This measurement from lensed emission near the event horizon is consistent with the presence of a central Kerr black hole, as predicted by the general theory of relativity.

Atomic cobalt on nitrogen-doped graphene for hydrogen generation
Huilong Fei, Juncai Dong, M. Josefina Arellano-Jiménez, Gonglan Ye +4 more
2015· Nature Communications1.6Kdoi:10.1038/ncomms9668

Reduction of water to hydrogen through electrocatalysis holds great promise for clean energy, but its large-scale application relies on the development of inexpensive and efficient catalysts to replace precious platinum catalysts. Here we report an electrocatalyst for hydrogen generation based on very small amounts of cobalt dispersed as individual atoms on nitrogen-doped graphene. This catalyst is robust and highly active in aqueous media with very low overpotentials (30 mV). A variety of analytical techniques and electrochemical measurements suggest that the catalytically active sites are associated with the metal centres coordinated to nitrogen. This unusual atomic constitution of supported metals is suggestive of a new approach to preparing extremely efficient single-atom catalysts.

Artificial intelligence: A powerful paradigm for scientific research
Yongjun Xu, Xin Liu, Xin Cao, Changping Huang +4 more
2021· The Innovation1.6Kdoi:10.1016/j.xinn.2021.100179

Y Artificial intelligence (AI) coupled with promising machine learning (ML) techniques well known from computer science is broadly affecting many aspects of various fields including science and technology, industry, and even our day-to-day life. The ML techniques have been developed to analyze high-throughput data with a view to obtaining useful insights, categorizing, predicting, and making evidence-based decisions in novel ways, which will promote the growth of novel applications and fuel the sustainable booming of AI. This paper undertakes a comprehensive survey on the development and application of AI in different aspects of fundamental sciences, including information science, mathematics, medical science, materials science, geoscience, life science, physics, and chemistry. The challenges that each discipline of science meets, and the potentials of AI techniques to handle these challenges, are discussed in detail. Moreover, we shed light on new research trends entailing the integration of AI into each scientific discipline. The aim of this paper is to provide a broad research guideline on fundamental sciences with potential infusion of AI, to help motivate researchers to deeply understand the state-of-the-art applications of AI-based fundamental sciences, and thereby to help promote the continuous development of these fundamental sciences.

Cytotoxicity of Carbon Nanomaterials:  Single-Wall Nanotube, Multi-Wall Nanotube, and Fullerene
Guang Jia, Haifang Wang, Lei Yan, Xiang Wang +4 more
2005· Environmental Science & Technology1.4Kdoi:10.1021/es048729l

A cytotoxicity test protocol for single-wall nanotubes (SWNTs), multi-wall nanotubes (with diameters ranging from 10 to 20 nm, MWNT10), and fullerene (C60) was tested. Profound cytotoxicity of SWNTs was observed in alveolar macrophage (AM) after a 6-h exposure in vitro. The cytotoxicity increases by as high as approximately 35% when the dosage of SWNTs was increased by 11.30 microg/cm2. No significant toxicity was observed for C60 up to a dose of 226.00 microg/cm2. The cytotoxicity apparently follows a sequence order on a mass basis: SWNTs > MWNT10 > quartz > C60. SWNTs significantly impaired phagocytosis of AM at the low dose of 0.38 microg/cm2, whereas MWNT10 and C60 induced injury only at the high dose of 3.06 microg/cm2. The macrophages exposed to SWNTs or MWNT10 of 3.06 microg/cm2 showed characteristic features of necrosis and degeneration. A sign of apoptotic cell death likely existed. Carbon nanomaterials with different geometric structures exhibit quite different cytotoxicity and bioactivity in vitro, although they may not be accurately reflected in the comparative toxicity in vivo.

Hadronic molecules
Feng-Kun Guo, C. Hanhart, Ulf-G. Meißner, Qian Wang +2 more
2018· Reviews of Modern Physics1.3Kdoi:10.1103/revmodphys.90.015004

Hadrons are composite particles made of quark and gluons. Interestingly, some excited hadronic states resemble the deuteron viewed as a barely bound neutron-proton system. Such hadronic molecules are spatially extended systems lying very close to decay thresholds. This work reviews the current experimental evidence for hadronic molecules and related theoretical descriptions, including effective field theories and lattice quantum chromodynamics.

Combined Measurement of the Higgs Boson Mass in<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mi>p</mml:mi><mml:mi>p</mml:mi></mml:math>Collisions at<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:msqrt><mml:mi>s</mml:mi></mml:msqrt><mml:mo>=</mml:mo><mml:mn>7</mml:mn></mml:math>and 8 TeV with the ATLAS and CMS Experiments
G. Aad, B. Abbott, J. Abdallah, O. Abdinov +4 more
2015· Physical Review Letters1.3Kdoi:10.1103/physrevlett.114.191803

A measurement of the Higgs boson mass is presented based on the combined data samples of the ATLAS and CMS experiments at the CERN LHC in the H→γγ and H→ZZ→4ℓ decay channels. The results are obtained from a simultaneous fit to the reconstructed invariant mass peaks in the two channels and for the two experiments. The measured masses from the individual channels and the two experiments are found to be consistent among themselves. The combined measured mass of the Higgs boson is m_{H}=125.09±0.21 (stat)±0.11 (syst) GeV.

Dark energy constraints from the cosmic age and supernova
Bo Feng, Xiulian Wang, Xinmin Zhang
2004· Physics Letters B1.3Kdoi:10.1016/j.physletb.2004.12.071

Using the low limit of cosmic ages from globular cluster and the white dwarfs: t0>12Gyr, together with recent new high redshift supernova observations from the HST/GOODS program and previous supernova data, we give a considerable estimation of the equation of state for dark energy, with uniform priors as weak as 0.2<Ωm<0.4 or 0.1<Ωmh2<0.16. We find cosmic age limit plays a significant role in lowering the upper bound on the variation amplitude of dark energy equation of state. We propose in this Letter a new scenario of dark energy dubbed quintom, which gives rise to the equation of state larger than −1 in the past and less than −1 today, satisfying current observations. In addition we have also considered the implications of recent X-ray gas mass fraction data on dark energy, which favors a negative running of the equation of state.

Technologies and perspectives for achieving carbon neutrality
Fang Wang, Jean Damascene Harindintwali, Zhizhang Yuan, Min Wang +4 more
2021· The Innovation1.3Kdoi:10.1016/j.xinn.2021.100180

Global development has been heavily reliant on the overexploitation of natural resources since the Industrial Revolution. With the extensive use of fossil fuels, deforestation, and other forms of land-use change, anthropogenic activities have contributed to the ever-increasing concentrations of greenhouse gases (GHGs) in the atmosphere, causing global climate change. In response to the worsening global climate change, achieving carbon neutrality by 2050 is the most pressing task on the planet. To this end, it is of utmost importance and a significant challenge to reform the current production systems to reduce GHG emissions and promote the capture of CO2 from the atmosphere. Herein, we review innovative technologies that offer solutions achieving carbon (C) neutrality and sustainable development, including those for renewable energy production, food system transformation, waste valorization, C sink conservation, and C-negative manufacturing. The wealth of knowledge disseminated in this review could inspire the global community and drive the further development of innovative technologies to mitigate climate change and sustainably support human activities.

Oxygen Vacancy Clusters Promoting Reducibility and Activity of Ceria Nanorods
Xiangwen Liu, Kebin Zhou, Lei Wang, Baoyi Wang +1 more
2009· Journal of the American Chemical Society1.3Kdoi:10.1021/ja808433d

CeO(2) is a catalytic material of exceptional technological importance, and the precise role of oxygen vacancies is crucial to the greater understanding of these oxide materials. In this work, two ceria nanorod samples with different types and distributions of oxygen vacancies were synthesized. A direct relationship between the concentration of the larger size oxygen vacancy clusters and the reducibility/reactivity of nanosized ceria was revealed. These results may be an important step in understanding and designing active sites at the surface of metal oxide catalytic materials.

Contributions of Phase, Sulfur Vacancies, and Edges to the Hydrogen Evolution Reaction Catalytic Activity of Porous Molybdenum Disulfide Nanosheets
Ying Yin, Jiecai Han, Yumin Zhang, Xinghong Zhang +4 more
2016· Journal of the American Chemical Society1.2Kdoi:10.1021/jacs.6b03714

Molybdenum disulfide (MoS2) is a promising nonprecious catalyst for the hydrogen evolution reaction (HER) that has been extensively studied due to its excellent performance, but the lack of understanding of the factors that impact its catalytic activity hinders further design and enhancement of MoS2-based electrocatalysts. Here, by using novel porous (holey) metallic 1T phase MoS2 nanosheets synthesized by a liquid-ammonia-assisted lithiation route, we systematically investigated the contributions of crystal structure (phase), edges, and sulfur vacancies (S-vacancies) to the catalytic activity toward HER from five representative MoS2 nanosheet samples, including 2H and 1T phase, porous 2H and 1T phase, and sulfur-compensated porous 2H phase. Superior HER catalytic activity was achieved in the porous 1T phase MoS2 nanosheets that have even more edges and S-vacancies than conventional 1T phase MoS2. A comparative study revealed that the phase serves as the key role in determining the HER performance, as 1T phase MoS2 always outperforms the corresponding 2H phase MoS2 samples, and that both edges and S-vacancies also contribute significantly to the catalytic activity in porous MoS2 samples. Then, using combined defect characterization techniques of electron spin resonance spectroscopy and positron annihilation lifetime spectroscopy to quantify the S-vacancies, the contributions of each factor were individually elucidated. This study presents new insights and opens up new avenues for designing electrocatalysts based on MoS2 or other layered materials with enhanced HER performance.

Neutrino physics with JUNO
Fengpeng An, Guangpeng An, Qi An, V. Antonelli +4 more
2016· Journal of Physics G Nuclear and Particle Physics1.2Kdoi:10.1088/0954-3899/43/3/030401

The Jiangmen Underground Neutrino Observatory (JUNO), a 20 kton multi-purpose\nunderground liquid scintillator detector, was proposed with the determination\nof the neutrino mass hierarchy as a primary physics goal. It is also capable of\nobserving neutrinos from terrestrial and extra-terrestrial sources, including\nsupernova burst neutrinos, diffuse supernova neutrino background, geoneutrinos,\natmospheric neutrinos, solar neutrinos, as well as exotic searches such as\nnucleon decays, dark matter, sterile neutrinos, etc. We present the physics\nmotivations and the anticipated performance of the JUNO detector for various\nproposed measurements. By detecting reactor antineutrinos from two power plants\nat 53-km distance, JUNO will determine the neutrino mass hierarchy at a 3-4\nsigma significance with six years of running. The measurement of antineutrino\nspectrum will also lead to the precise determination of three out of the six\noscillation parameters to an accuracy of better than 1\\%. Neutrino burst from a\ntypical core-collapse supernova at 10 kpc would lead to ~5000\ninverse-beta-decay events and ~2000 all-flavor neutrino-proton elastic\nscattering events in JUNO. Detection of DSNB would provide valuable information\non the cosmic star-formation rate and the average core-collapsed neutrino\nenergy spectrum. Geo-neutrinos can be detected in JUNO with a rate of ~400\nevents per year, significantly improving the statistics of existing geoneutrino\nsamples. The JUNO detector is sensitive to several exotic searches, e.g. proton\ndecay via the $p\\to K^++\\bar\\nu$ decay channel. The JUNO detector will provide\na unique facility to address many outstanding crucial questions in particle and\nastrophysics. It holds the great potential for further advancing our quest to\nunderstanding the fundamental properties of neutrinos, one of the building\nblocks of our Universe.

Cellular Uptake, Intracellular Trafficking, and Cytotoxicity of Nanomaterials
Feng Zhao, Ying Zhao, Ying Zhao, Ying Liu +4 more
2011· Small1.2Kdoi:10.1002/smll.201100001

The interactions of nanoparticles with the soft surfaces of biological systems like cells play key roles in executing their biomedical functions and in toxicity. The discovery or design of new biomedical functions, or the prediction of the toxicological consequences of nanoparticles in vivo, first require knowledge of the interplay processes of the nanoparticles with the target cells. This article focusses on the cellular uptake, location and translocation, and any biological consequences, such as cytotoxicity, of the most widely studied and used nanoparticles, such as carbon-based nanoparticles, metallic nanoparticles, and quantum dots. The relevance of the size and shape, composition, charge, and surface chemistry of the nanoparticles in cells is considered. The intracellular uptake pathways of the nanoparticles and the cellular responses, with potential signaling pathways activated by nanoparticle interactions, are also discussed.