Philips (India)

Abstract “…. For the truth of the conclusions of physical science, observation is the supreme Court of Appeal….” (Sir Arthur Eddington, The Philosophy of Physical Science.) In this paper we shall review the theoretical and experimental results obtained on simple magnetic model systems. We shall consider the Heisenberg, XY and Ising type of interaction (ferro and antiferromagnetic), on magnetic lattices of dimensionality 1, 2 and 3. Particular attention will be paid to the approximation of these model systems in real crystals, viz. how they can be realized or be expected to exist in nature. A large number of magnetic compounds which, according to the available experimental information, meet the requirements set by one or the other of the various models are considered and their properties discussed. Many examples will be given that demonstrate to what extent experiments on simple magnetic systems support theoretical descriptions of magnetic ordering phenomena and contribute to their understanding. It will also be indicated in which direction there is a need and/or a possibility for future work.

(1926). LXXXVIII. On “relaxation-oscillations”. The London, Edinburgh, and Dublin Philosophical Magazine and Journal of Science: Vol. 2, No. 11, pp. 978-992.

An unprecedented transformation in the design, deployment, and application of short-range wireless devices and services is in progress today. This trend is in line with the imminent transition from third- to fourth-generation radio systems, where heterogeneous environments are expected to prevail eventually. A key driver in this transition is the steep growth in both demand and deployment of WLANs/WPANs based on the wireless standards within the IEEE 802 suite. Today, these short-range devices and networks operate mainly standalone in indoor home and office environments or large enclosed public areas, while their integration into the wireless wide-area infrastructure is still nearly nonexistent and far from trivial. This status quo in the short-range wireless application space is about to be disrupted by novel devices and systems based on the emerging UWB radio technology with the potential to provide solutions for many of today's problems in the areas of spectrum management and radio system engineering. The approach employed by UWB radio devices is based on sharing already occupied spectrum resources by means of the overlay principle, rather than looking for still available but possibly unsuitable new bands. This novel radio technology has received legal adoption by the regulatory authorities in the United States, and efforts to achieve this status in Europe and Asia are underway. This article discusses both the application potential and technical challenges presented by UWB radio as an unconventional but promising new wireless technology.

This paper discusses the problem of receive antenna subset selection in multiple-input multiple-output spatial multiplexing (MIMO-SM) systems. We develop selection algorithms for maximizing the channel capacity. One algorithm in particular allows tractable statistical analysis of performance. We leverage this to prove that the capacity of the system through receive antenna selection is statistically lower bounded by the capacity of a set of parallel independent single input multiple output (SIMO) channels, each with selection diversity. This provides the crucial step in proving the next main result: The diversity order achievable through antenna selection is the same as that of the full system. The result sets up strong motivation for introducing receive selection in MIMO-SM systems. The remainder of the paper discusses selection algorithms for two popular MIMO-SM systems, namely, ordered successive interference cancellation with independently encoded layers and minimum mean square error (MMSE) receiver with joint encoding of data streams. Extensive Monte Carlo simulations are presented to validate and demonstrate performance.

The main objective of core-based IC design is improvement of design efficiency and time-to-market. In order to prevent test development from becoming the bottleneck in the entire development trajectory, reuse of pre-computed tests for the reusable pre-designed cores is mandatory. The core user is responsible for translating the test at core level into a test at chip level. A standardized test access mechanism eases this task, therefore contributing to the plug-n-play character of core-based design. This paper presents the concept of a structured test access mechanism for embedded cores. Reusable IP modules are wrapped in a TESTSHELL. Test data access from chip pins to TESTSHELL and vice versa is provided by the TESTRAIL, while the operation of the TESTSHELL is controlled by a dedicated test control mechanism (TCM). Both TESTRAIL as well as TCM are standardized, but open for extensions.

We present a programming interface called YAPI to model signal processing applications as process networks. The purpose of YAPI is to enable the reuse of signal processing applications and the mapping of signal processing applications onto heterogeneous systems that contain hardware and software components. To this end, YAPI separates the concerns of the application programmer, who determines the functionality of the system, and the system designer, who determines the implementation of the functionality. The proposed model of computation extends the existing model of Kahn process networks with channel selection to support non-deterministic events. We provide an efficient implementation of YAPI in the form of a C++ run-time library to execute the applications on a workstation. Subsequently, the applications are used by the system designer as input for mapping and performance analysis in the design of complex signal processing systems. We evaluate this methodology on the design of a digital video broadcast system-on-chip.

This article describes the use of personalized short text messages (SMS) to reduce snacking. First, we describe the development and validation ( N = 215) of a questionnaire to measure individual susceptibility to different social influence strategies. To evaluate the external validity of this Susceptibility to Persuasion Scale (STPS) we set up a two week text-messaging intervention that used text messages implementing social influence strategies as prompts to reduce snacking behavior. In this experiment ( N = 73) we show that messages that are personalized (tailored) to the individual based on their scores on the STPS, lead to a higher decrease in snacking consumption than randomized messages or messages that are not tailored (contra-tailored) to the individual. We discuss the importance of this finding for the design of persuasive systems and detail how designers can use tailoring at the level of social influence strategies to increase the effects of their persuasive technologies.

Ambient intelligence opens up a world of unprecedented experiences. The interaction of people with electronic devices will change as context awareness, natural interfaces, and ubiquitous availability of information come to fruition. Ambient intelligence is going to impose major challenges on multimedia research. Distributed multimedia applications and their processing on embedded static and mobile platforms will play a major role in the development of ambient-intelligent environments. The requirements that ambient-intelligent multimedia applications impose on the mechanisms users apply to interact with media call for paradigms substantially different from contemporary interaction concepts. The complexity of media will continually increase in terms of volume and functionality, thus introducing a need for simplicity and ease of use. Therefore, the massively distributed, integrated use of media will require replacing well-known interaction vehicles, such as remote control and menu-driven search and control, with novel more intuitive, and natural concepts. This article reviews the concept of ambient intelligence and elaborates on its relation with multimedia. (The "Advances in media processing" sidebar gives insight into the developments that have set the stage for this new step forward.) The emphasis is on qualitative aspects, highlighting those elements that play a role in realizing ambient intelligence. Multimedia processing techniques and applications are key to realizing ambient intelligence, and they introduce major challenges to the design and implementation of both media-processing platforms and multimedia applications. Technology will not be the limiting factor in realizing ambient intelligence. The ingredients to let the computers disappear are already available, but the true success of the paradigm will depend on the ability to develop concepts that allow natural interaction with digital environments. We must build these digital environments with the invisible technology of the forthcoming century. The role of intelligent algorithms in this respect is apparent because it is the key enabling factor for realizing natural interaction.

When sensory input allows for multiple, competing perceptual interpretations, observers' perception can fluctuate over time, which is called bistable perception. Imaging studies in humans have revealed transient responses in a right-lateralized network in the frontal-parietal cortex (rFPC) around the time of perceptual transitions between interpretations, potentially reflecting the neural initiation of transitions. We investigated the role of this activity in male human observers, with specific interest in its relation to the temporal structure of transitions, which can be either instantaneous or prolonged by periods during which observers experience a mix of both perceptual interpretations. Using both bistable apparent motion and binocular rivalry, we show that transition-related rFPC activity is larger for transitions that last longer, suggesting that rFPC remains active as long as a transition lasts. We also replicate earlier findings that rFPC activity during binocular rivalry transitions exceeds activity during yoked transitions that are simulated using video replay. However, we show that this established finding holds only when perceptual transitions are replayed as instantaneous events. When replay, instead, depicts transitions with the actual durations reported during rivalry, yoked transitions and genuine rivalry transitions elicit equal activity. Together, our results are consistent with the view that at least a component of rFPC activation during bistable perception reflects a response to perceptual transitions, both real and yoked, rather than their cause. This component of activity could reflect the change in sensory experience and task demand that occurs during transitions, which fits well with the known role of these areas in attention and decision making.

<p><a href="http://jon.osa.org/virtual_issue.cfm?vid=54">Focus Issue on Orthogonal-Frequency-Division Multiplexed Communications Systems and Networks</a></p>We discuss the realization and performance of polarization-division-multiplexed orthogonal frequency division multiplexing (PDM-OFDM) for long-haul transmission systems. Polarization demultiplexing of the PDM signal at the receiver is realized by employing a multiple-input multiple-output (MIMO) detector. Using a recirculating loop a long-haul transmission experiment is reported of 52.5 Gbits/s PDM-OFDM (40 Gbits/s after coding) over 4160 km of standard single-mode fiber (SSMF). In this transmission experiment, 16 wavelength-division-multiplexed (WDM) channels are transmitted at 50 GHz channel spacing, and we show that MIMO processing in the receiver enables both polarization demultiplexing and a large PMD tolerance.

The purpose of this project was to examine the relationship between a subjective response to a lit environment and its luminance distribution as a contribution to improving lighting design. The study was made using a full-scale mock-up conference room lit in 18 different ways. Observer subjective assessments were examined using factor analysis and this identified two main factors: 'visual interest' and 'visual lightness'. The experiment showed that these two factors could respectively be described by the luminance contrast and the average luminance within a horizontal band 40° wide and centred at normal eye height. The results suggest minimum values for these two parameters which are likely to be necessary for a lit environment to appear both 'interesting' and 'light'.

BACKGROUND: Prior studies evaluating the efficacy of catheter ablation of ventricular tachycardia (VT) among patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) have reported varied outcomes. More recently, studies have suggested that an epicardial ablation is necessary for improved outcomes after catheter ablation of VT. The overall objective of the present study was to assess the efficacy of radiofrequency catheter ablation (RFA) of VT in ARVD/C, with particular focus on newer ablation strategies, including epicardial catheter ablation. METHODS AND RESULTS: The study population included 87 patients with ARVD/C who underwent a total of 175 RFA procedures between 1992 and 2011 at 80 different electrophysiology centers. Recurrence of VT following RFA and effect of RFA on the burden of VT were assessed. The mean age of the cohort was 38±13 years. Over a mean follow-up of 88.3±66 months, the overall freedom from VT of the 175 procedures was 47%, 21%, and 15%, at 1, 5, and 10 years, respectively. The cumulative freedom from VT following epicardial RFA was 64% and 45% at 1 and 5 years, respectively, which was significantly longer than endocardial RFA (P=0.021). Survival free of VT among procedures with 3D electroanatomic mapping was significantly longer compared to those without (P=0.016). Burden of VT was reduced irrespective of the ablation strategy (P<0.001). CONCLUSIONS: Although VT recurrences are common, RFA results in a significant reduction in the burden of VT in patients with ARVD/C. Further, although the use of 3D electroanatomic mapping systems and epicardial ablation strategies are associated with longer survival free of VT, recurrence rates remain considerable.

The luminescence properties of Eu(2+) doped strontium aluminates are reported and reviewed for a variety of aluminates, viz. SrAl12O19, SrAl4O7, Sr4Al14O25, SrAl2O4 and Sr3Al2O6. The aim of the research is to investigate the role of local coordination and covalency of the aluminate host lattice, related to the Sr/Al ratio, on the optical properties of the Eu(2+) ion. The UV and VUV excited luminescence spectra as well as luminescence decay curves were recorded to characterize the luminescence properties of the investigated aluminates. The emission of Eu(2+) ions varies over a wide spectral range, from ultraviolet (UV) to red, for the series of aluminates. The variation in emission color can be related to the crystal-field splitting of the 5d levels and the covalent interaction with the surrounding oxygen anions. In the least covalent material, viz. SrAl12O19:Eu(2+), narrow line emission due to the (6)P7/2-(8)S7/2 transition occurs at 4 K, indicating that the 4f(6)5d excited state is situated above the (6)P7/2(4f(7)) excited state around 360 nm. The most alkaline material, viz. Sr3Al2O6:Eu(2+) is the most covalent host and exhibits several d-f emission bands in the yellow to red spectral range due to the Eu(2+) ions located on different crystallographic Sr(2+) sites. The Eu(2+) emission spectra in the other aluminates confirm the trend that with increasing Sr/Al ratio the Eu(2+) emission shifts to longer wavelengths. Interesting differences are observed for the Eu(2+) from different crystallographic sites which cannot always be related with apparent differences in the first oxygen coordination sphere. The discussion gives insight into how in a similar class of materials, strontium aluminates, the emission color of Eu(2+) can be tuned over a wide spectral region.

Photodynamic therapy (PDT) is a promising therapeutic modality for treatment of solid tumors. In this study, third-generation aryl ether dendrimer porphyrins (DPs) with either 32 quaternary ammonium groups (32(+)DPZn) or 32 carboxylic groups (32(-)DPZn) were evaluated as a novel, supramolecular class of photosensitizers for PDT. DPs showed a different cell-association profile depending on the positive or negative charge on the periphery, and both DPs eventually localized in membrane-limited organelles. In contrast, protoporphyrin IX (PIX), which is a hydrophobic and relatively low molecular weight photosensitizer used as a control in this study, diffused through the cytoplasm except the nucleus. Confocal fluorescent imaging using organelle-specific dyes indicated that PIX induced severe photodamage to disrupt membranes and intracellular organelles, including the plasma membrane, mitochondrion, and lysosome. On the other hand, cells treated with DPs kept the characteristic fluorescent pattern of such organelles even after photoirradiation. However, notably 32(+)DPZn achieved remarkably higher (1)O(2)-induced cytotoxicity against LLC cells than PIX. Furthermore, both dendrimer porphyrins had far lower dark toxicity as compared with PIX, demonstrating their highly selective photosensitizing effect in combination with a reduced systemic toxicity.

The problem of CMOS op-amp circuit sizing is addressed here. Given a circuit and its performance specifications, the goal is to automatically determine the device sizes in order to meet the given performance specifications while minimizing a cost function, such as a weighted sum of the active area and power dissipation. The approach is based on the observation that the first order behavior of a MOS transistor in the saturation region is such that the cost and the constraint functions for this optimization problem can be modeled as posynomial in the design variables. The problem is then solved efficiently as a convex optimization problem. Second order effects are then handled by formulating the problem as one of solving a sequence of convex programs. Numerical experiments show that the solutions to the sequence of convex programs converge to the same design point for widely varying initial guesses. This strongly suggests that the approach is capable of determining the globally optimal solution to the problem. Accuracy of performance prediction in the sizing program (implemented in MATLAB) is maintained by using a newly proposed MOS transistor model and verified against detailed SPICE simulation.

One of the most common types of cancer in men is prostate cancer (PCa). Biopsies guided by bi-parametric magnetic resonance imaging (MRI) can aid PCa diagnosis. Previous works have mostly focused on either detection or classification of PCa from MRI. In this work, however, we present a neural network that simultaneously detects and grades cancer tissue in an end-to-end fashion. This is more clinically relevant than the classification goal of the ProstateX-2 challenge. We used the dataset of this challenge for training and testing. We use a 2D U-Net with MRI slices as input and lesion segmentation maps that encode the Gleason Grade Group (GGG), a measure for cancer aggressiveness, as output. We propose a method for encoding the GGG in the model target that takes advantage of the fact that the classes are ordinal. Furthermore, we evaluate methods for incorporating prostate zone segmentations as prior information, and ensembling techniques. The model scored a voxel-wise weighted kappa of 0.446 ±0.082 and a Dice similarity coefficient for segmenting clinically significant cancer of 0.370 ±0.046, obtained using 5-fold cross-validation. The lesion-wise weighted kappa on the ProstateX-2 challenge test set was 0.13 ±0.27. We show that our proposed model target outperforms standard multiclass classification and multi-label ordinal regression. Additionally, we present a comparison of methods for further improvement of the model performance.

Atomic layer deposition (ALD) is used in applications where inorganic material layers with uniform thickness down to the nanometer range are required. For such thicknesses, the growth mode, defining how the material is arranged on the surface during the growth, is of critical importance. In this work, the growth mode of the zirconium tetrachloride∕water and the trimethyl aluminum∕water ALD process on hydrogen-terminated silicon was investigated by combining information on the total amount of material deposited with information on the surface fraction of the material. The total amount of material deposited was measured by Rutherford backscattering, x-ray fluorescence, and inductively coupled plasma–optical emission spectroscopy, and the surface fractions by low-energy ion scattering. Growth mode modeling was made assuming two-dimensional growth or random deposition (RD), with a “shower model” of RD recently developed for ALD. Experimental surface fractions of the ALD-grown zirconium oxide and aluminum oxide films were lower than the surface fractions calculated assuming RD, suggesting the occurrence of island growth. Island growth was confirmed with transmission electron microscopy (TEM) measurements, from which the island size and number of islands per unit surface area could also be estimated. The conclusion of island growth for the aluminum oxide deposition on hydrogen-terminated silicon contradicts earlier observations. In this work, physical aluminum oxide islands were observed in TEM after 15 ALD reaction cycles. Earlier, thicker aluminum oxide layers have been analyzed, where islands have not been observed because they have already coalesced to form a continuous film. The unreactivity of hydrogen-terminated silicon surface towards the ALD reactants, except for reactive defect areas, is proposed as the origin of island growth. Consequently, island growth can be regarded as “undesired surface-selective ALD.”

The Unified Modeling Language has attracted many organizations and practitioners. UML is now the de facto modeling language for software development. Several features account for its popularity: it's a standardized notation, rich in expressivity; UML 2.0 provides 13 diagram types that enable modeling several different views and abstraction levels. Furthermore, UML supports domain-specific extensions using stereotypes and tagged values. Finally, several case tools integrate UML modeling with other tasks such as generating code and reverse-engineering models from code. Our study focused on UML use and model quality in actual projects rather than on its adequacy as a notation or language.

Employees of a large industry were screened for the presence of coronary risk factors. A total of 204 employees, aged 35-64 years, with two or more such factors (serum cholesterol concentration greater than or equal to 6.3 mmol/l (243.6 mg/100 ml), blood pressure greater than or equal to 140/90 mm Hg, and current cigarette consumption greater than or equal to 10 cigarettes a day) were randomly allocated to a biofeedback group receiving training in relaxation and management of stress or a control group. Both groups received simple health education literature. After eight weeks of training, and again eight months later, the biofeedback group showed a significantly greater fall in systolic and diastolic blood pressures than the control group (p less than 0.001). Plasma renin activity and plasma aldosterone concentration were measured in a subsample at entry to the study and again at eight weeks and eight months; both showed a greater reduction in the biofeedback compared with the control group at eight weeks' follow-up. The greater reduction in blood pressure in the subjects in the biofeedback group compared with the control group (11.0 mm Hg systolic and 8.8 mm Hg diastolic), persisting eight months after the training, suggests that relaxation-based behavioural methods might be offered as a first-time treatment to patients with mild hypertension.

By modifying a clinical ultrasound array system, we develop a novel handheld photoacoustic probe for image-guided needle biopsy. The integration of optical fiber bundles for pulsed laser light delivery enables photoacoustic image-guided insertion of a needle into rat axillary lymph nodes with accumulated indocyanine green (ICG). Strong photoacoustic contrast of the needle is achieved. After subcutaneous injection of the dye in the left forepaw, sentinel lymph nodes are easily detected, in vivo and in real time, beneath 2-cm-thick chicken breast overlaying the axillary region. ICG uptake in axillary lymph nodes is confirmed with fluorescence imaging both in vivo and ex vivo. These results demonstrate the clinical potential of this handheld photoacoustic system for facile identification and needle biopsy of sentinel lymph nodes for cancer staging and metastasis detection in humans.