The Research Council of Norway

ABSTRACT We present a compelling rationale for defining agroecology as the ecology of food systems. Our purpose is to provide a framework that will guide research, education, and action in the multiple and interacting facets of an increasingly complex global agriculture and food system. To accomplish such goals, it is essential to build bridges and connections among and beyond our disciplines in production agriculture, as well as beyond the farm gate into the rural landscape and community. Fields of sociology, anthropology, environmental sciences, ethics, and economics are crucial to the mix. They provide additional vantage points from which we can view the food system anew, as well as insights on how to establish valuation criteria beyond neoclassical economics. Examples from Mexico, California, and the Nordic Region are used to illustrate the successful implementation of this educational strategy in universities. Design of individual farms using principles of ecology is expanded to the levels of landscape, community, and bioregion, with emphasis on uniqueness of place and the people and other species that inhabit that place. We conclude that defining agroecology as the ecology of food systems will foster the development of broader interdisciplinary research teams and attractive systems-based courses for tomorrow's best students. In contrast to the narrow focus on crop-soil interactions, this definition will help us raise higher-level research questions whose solutions will advance the development of a sustainable agriculture and food system. KEYWORDS: Agricultural systemsholistic researchaction learninginterdisciplinary studies

The utilisation of dietary carbohydrates and their effects on fish metabolism are reviewed. Details on how dietary carbohydrates affect growth, feed utilisation and deposition of nutrients are discussed. Variations in plasma glucose concentrations emphasizing results from glucose tolerance tests, and the impact of adaptation diets are interpreted in the context of secondary carbohydrate metabolism. Our focus then shifts to selected aspects of hormonal regulation of carbohydrate metabolism and dietary carbohydrates and their variable effects on glycogen and glucose turnover. We analyse the interaction of carbohydrates with other nutrients, especially protein and protein sparing, and de novo synthesis of lipids, and finish by discussing the correlation of dietary carbohydrates with fish health.

Abstract Global climate change is expected to shift species ranges polewards, with a risk of range contractions and population declines of especially high‐Arctic species. We built species distribution models for Svalbard‐nesting pink‐footed geese to relate their occurrence to environmental and climatic variables, and used the models to predict their distribution under a warmer climate scenario. The most parsimonious model included mean May temperature, the number of frost‐free months and the proportion of moist and wet moss‐dominated vegetation in the area. The two climate variables are indicators for whether geese can physiologically fulfil the breeding cycle or not and the moss vegetation is an indicator of suitable feeding conditions. Projections of the distribution to warmer climate scenarios propose a large north‐ and eastward expansion of the potential breeding range on Svalbard even at modest temperature increases (1 and 2 °C increase in summer temperature, respectively). Contrary to recent suggestions regarding future distributions of Arctic wildlife, we predict that warming may lead to a further growth in population size of, at least some, Arctic breeding geese.

The emergence of agriculture in the Near East also involved the domestication of einkorn wheat. Phylogenetic analysis that was based on the allelic frequency at 288 amplified fragment length polymorphism molecular marker loci indicates that a wild group of Triticum monococcum boeoticum lines from the Karacadağ mountains (southeast Turkey) is the likely progenitor of cultivated einkorn varieties. Evidence from archeological excavations of early agricultural settlements nearby supports the conclusion that domestication of einkorn wheat began near the Karacadağmountains.

ABSTRACT BACKGROUND WHO expert groups recommended mortality trials in hospitalized COVID-19 of four re-purposed antiviral drugs. METHODS Study drugs were Remdesivir, Hydroxychloroquine, Lopinavir (fixed-dose combination with Ritonavir) and Interferon-β1a (mainly subcutaneous; initially with Lopinavir, later not). COVID-19 inpatients were randomized equally between whichever study drugs were locally available and open control (up to 5 options: 4 active and local standard-of-care). The intent-to-treat primary analyses are of in-hospital mortality in the 4 pairwise comparisons of each study drug vs its controls (concurrently allocated the same management without that drug, despite availability). Kaplan-Meier 28-day risks are unstratified; log-rank death rate ratios (RRs) are stratified for age and ventilation at entry. RESULTS In 405 hospitals in 30 countries 11,266 adults were randomized, with 2750 allocated Remdesivir, 954 Hydroxychloroquine, 1411 Lopinavir, 651 Interferon plus Lopinavir, 1412 only Interferon, and 4088 no study drug. Compliance was 94-96% midway through treatment, with 2-6% crossover. 1253 deaths were reported (at median day 8, IQR 4-14). Kaplan-Meier 28-day mortality was 12% (39% if already ventilated at randomization, 10% otherwise). Death rate ratios (with 95% CIs and numbers dead/randomized, each drug vs its control) were: Remdesivir RR=0.95 (0.81-1.11, p=0.50; 301/2743 active vs 303/2708 control), Hydroxychloroquine RR=1.19 (0.89-1.59, p=0.23; 104/947 vs 84/906), Lopinavir RR=1.00 (0.79-1.25, p=0.97; 148/1399 vs 146/1372) and Interferon RR=1.16 (0.96-1.39, p=0.11; 243/2050 vs 216/2050). No study drug definitely reduced mortality (in unventilated patients or any other subgroup of entry characteristics), initiation of ventilation or hospitalisation duration. CONCLUSIONS These Remdesivir, Hydroxychloroquine, Lopinavir and Interferon regimens appeared to have little or no effect on hospitalized COVID-19, as indicated by overall mortality, initiation of ventilation and duration of hospital stay. The mortality findings contain most of the randomized evidence on Remdesivir and Interferon, and are consistent with meta-analyses of mortality in all major trials. (Funding: WHO. Registration: ISRCTN83971151 , NCT04315948 )

Traditional supplements of selenium generally have a low degree of absorption and increased toxicity. Therefore, it is imperative to develop innovative systems as transporters of selenium compounds, which would raise the bioavailability of this element and allow its controlled release in the organism. Nanoscale selenium has attracted a great interest as a food additive especially in individuals with selenium deficiency, but also as a therapeutic agent without significant side effects in medicine. This review is focused on the incorporation of nanotechnological applications, in particular exploring the possibilities of a more effective way of administration, especially in selenium-deficient organisms. In addition, this review summarizes the survey of knowledge on selenium nanoparticles, their biological effects in the organism, advantages, absorption mechanisms, and nanotechnological applications for peroral administration.

We prove that the two algorithms given in the literature for partial least squares regression are equivalent, and use this equivalence to give an explicit formula for the resulting prediction equation. This in turn is used to investigate the regression method from several points of view. Its relation to principal component regression is clearified, and some heuristic arguments are given to explain why partial least squares regression often needs fewer factors to give its optimal prediction.

Mean tree height, dominant height, mean diameter, stem number, basal area and timber volume of 116 georeferenced field sample plots were estimated from various canopy height and canopy density metrics derived by means of a small-footprint laser scanner over young and mature forest stands using regression analysis. The sample plots were distributed systematically throughout a 6500 ha study area, and the size of each plot was 232.9 m2. Regressions for coniferous forest explained 60–97% of the variability in ground reference values of the six studied characteristics. A proposed practical two-phase procedure for prediction of corresponding characteristics of entire forest stands was tested. Fifty-seven test plots within the study area with a size of approximately 3740 m2 each were divided into 232.9 m2 regular grid cells. The six examined characteristics were predicted for each grid cell from the corresponding laser data using the estimated regression equations. Average values for each test plot were computed and compared with ground-based estimates measured over the entire plot. The bias and standard deviations of the differences between predicted and ground reference values (in parentheses) of mean height, dominant height, mean diameter, stem number, basal area and volume were −0.58 to −0.85 m (0.64–1.01 m), −0.60 to −0.99 m (0.67–0.84 m), 0.15–0.74 cm (1.33–2.42 cm), 34–108 ha−1 (97–466 ha−1), 0.43–2.51 m2 ha−1 (1.83–3.94 m2 ha−1) and 5.9–16.1 m3 ha−1 (15.1–35.1 m3 ha−1), respectively.

Abstract Modified atmosphere packaging (MAP) extends shelf-life of most fishery products by inhibiting bacterial growth and oxidative reactions. The achievable extension of shelf-life depends on species, fat content, initial microbial population, gas mixture, the ratio of gas volume to product volume, and most importantly, storage temperature. The shelf-life of fishery products is usually limited by microbial activity, although for some fatty fishes or at superchilled storage, it can be limited by nonmicrobial activity. Packaging of fishery products under modified atmospheres (MA) increases shelf-life compared with those packaged under air, but confers little or no additional shelf-life increase compared with vacuum packaging. The specific spoilage organism (SSO) of MA packaged cod at 0 °C has been found to be Photobacterium phosphoreum. Whether or not this bacterium is the general SSO for all marine temperate fishes at different storage temperatures and under various CO2/N2/O2 mixtures needs to be resolved. Without proper control of storage temperature, the benefits of MAP may be lost. Higher temperatures inevitably lead to less dissolved CO2 in the product and consequently loss of inhibitory effect, which may result in higher microbial and enzymatic activity, and uncertainties concerning the microbial safety, as food-borne pathogens might be present in the product.

Antibacterial drugs are among the most commonly used medications in the world. Tetracycline is a widely used antibiotic for human and animal therapy due to its broad-spectrum activity, high effectiveness, and reasonable cost. The indications for treatment with tetracycline include pneumonia, bone and joint infections, infectious disorders of the skin, sexually transmitted and gastrointestinal infections. However, tetracycline has become a serious threat to the environment because of its overuse by humans and veterinarians and weak ability to degrade. Tetracycline is capable of accumulating along the food chain, causing toxicity to the microbial community, encouraging the development and spread of antibiotic resistance, creating threats to drinking and irrigation water, and disrupting microbial flora in the human intestine. It is essential to address the negative impact of tetracycline on the environment, as it causes ecological imbalance. Ineffective wastewater systems are among the main reasons for the increased antibiotic concentrations in aquatic sources. It is possible to degrade tetracycline by breaking it down into small molecules with less harmful or nonhazardous effects. A range of methods for physical, chemical, and biological degradation exists. The review will discuss the negative effects of tetracycline consumption on the aquatic environment and describe available removal methods.

When a large number of tests are made, possibly on the same data, it is proposed to base a simultaneous evaluation of all the tests on a plot of cumulative P-values using the observed significance probabilities. The points corresponding to true null hypotheses should form a straight line, while those for false null hypotheses should deviate from this line. The line may be used to estimate the number of true hypotheses. The properties of the method are studied in some detail for the problems of comparing all pairs of means in a one-way layout, testing all correlation coefficients in a large correlation matrix, and the evaluation of all 2×2 subtables in a contingency table. The plot is illustrated on real data.

Abstract This paper reports results from a study of resource degradation and conservation behavior of peasant households in a degraded part of the Ethiopian highlands. Peasant households' choice of conservation technologies is modeled as a two-stage process: recognition of the erosion problem, and adoption and level of use of control practices. An ordinal logit model is used to explain parcel-level perception of the threat of the erosion problem and the extent of use of conservation practices. Results show the importance of perception of the threat of soil erosion, household, land and farm characteristics; perception of technology-specific attributes, and land quality differentials in shaping conservation decisions of peasants. Furthermore, where poverty is widespread and appropriate support policies are lacking, results indicate that population pressure per se is unable to encourage sustainable land use. The challenge of breaking the poverty-environment trap and initiating sustainable intensification thus require policy incentives and technologies that confer short-term benefits to the poor while conserving the resource base.

The Self-Perception Profile for Adolescents (SPPA; Harter, 1988) was administered to a national representative sample of 11,315 Norwegian adolescents of the ages 13 to 20. The original version of SPPA has an idiosyncratic and time-consuming item format, describing two adolescents with opposite characteristics on each item. A revised version of SPPA was developed using only one statement for each item. The original SPPA was administered to a random subsample of 880 subjects, whereas the rest of the total sample completed the revised edition. Concerning the original SPPA, results showed low to adequate reliability and poor replication of the factorial pattern. However, low correlations with the Marlowe-Crowne Social Desirability Index were obtained, and the construct validity was supported. Concerning the revised edition, the a priori factorial pattern was replicated. Further, it had substantially better reliability, better convergent validity, and better factorial validity than the original version. The discriminant validity and the contamination by social desirability bias were the same for both versions. The data thus indicate that there is no need to retain the time-consuming and cumbersome item format of the original SPPA.

Referee: Mr. Dick Fitzgerald, Ph.D., Life Science Department, University of Limerick, Limerick, Ireland After a brief description of the properties of bioactive peptides, the proteolytic activation of the bioactive sequences from milk protein precursors is discussed. The ability of proteolytic enzymes from various sources, especially from lactic acid bacteria, to release bioactive peptides and the physiological and biotechnological significance of these peptides in dairy products are reviewed.

Tryptophan (Trp) is an amino acid and an essential component of the human diet. It plays a crucial role in many metabolic functions. Clinicians can use Trp levels in the course of diagnosing various metabolic disorders and the symptoms associated with those diseases. Furthermore, supplementation with this amino acid is considered in the treatment of depression and sleep disorders, mainly due to the Trp relationship with the synthesis of serotonin (5-HT) and melatonin. It is also used in helping to resolve cognitive disorders, anxiety, or neurodegenerative diseases. Reduced secretion of serotonin is associated with autism spectrum disorder, obesity, anorexia and bulimia nervosa, and other diseases presenting peripherals symptoms. The literature strongly suggests that Trp has a significant role in the correct functionality of the brain-gut axis and immunology. This information leads to the consideration of Trp as an essential dietary component due to its role in the serotonin pathway. A reduced availability of Trp in diet and nutraceutical supplementation should be considered with greater concern than one might expect. This paper constitutes a review of the more salient aspects gleaned from the current knowledge base about the role of Trp in diseases, associated nutritional disorders, and food science, in general.

In Arabidopsis flowering is accelerated by reduced red:far-red (R:FR) ratio which signals the presence of neighbouring vegetation. Hastened flowering is one component of the shade-avoidance syndrome of responses, which alter many aspects of development in response to the threat of potential competition. Of the red/far-red-absorbing photoreceptors it is phyB that plays the most prominent role in shade-avoidance, although other related phytochromes act redundantly with phyB. It is well established that the phyB mutant has a constitutively early flowering phenotype. However, we have shown that the early flowering phenotype of phyB is temperature-dependent. We have established that this temperature-sensitive flowering response defines a pathway that appears to be independent of the autonomous-FLC pathway. Furthermore, we have demonstrated that the phytochromes control the expression of the floral promoter FT. We have also shown that other phyB-controlled responses, including petiole elongation, are not sensitive to the same temperature change. This suggests that discrete pathways control flowering and petiole elongation, components of the shade-avoidance response. This work provides an insight into the phytochrome and temperature interactions that maintain flowering control.

Bacteria were released and separated from soil by a simple blending-centrifugation procedure. The percent yield of bacterial cells (microscopic counts) in the supernatants varied over a wide range depending on the soil type. The superantants contained large amounts of noncellular organic material and clay particles. Further purification of the bacterial cells was obtained by centrifugation in density gradients, whereby the clay particles and part of the organic materials sedimented. A large proportion of the bacteria also sedimented through the density gradient, showing that they had a buoyant density above 1.2 g/ml. Attachment to clay minerals and humic material may account for this apparently high buoyant density. The percent yield of cells was negatively correlated with the clay content of the soils, whereas the purity was positively correlated with it. The cell size distribution and the relative frequency of colony-forming cells were similar in the soil homogenate, the supernatants after blending-centrifugation, and the purified bacterial fraction. In purified bacterial fraction from a clay loam, the microscopically measured biomass could account for 20 to 25% of the total C and 30 to 40% of the total N as cellular C and N. The amount of cellular C and N may be higher, however, owing to an underestimation of the cell diameter during fluorescence. A part of the contamination could be ascribed to extracellular structures as well as partly decayed cells, which were not revealed by fluorescence microscopy.

1. An experiment was conducted to study the effects of inclusion of oat hulls in diets based on whole or ground wheat for broilers. Effects of wood shavings on layers were investigated in a further experiment. 2. Inclusion of oat hulls in wheat-based broiler diets did not affect weight gain. Feed conversion efficiency (FCE), corrected for insoluble fibre contents, was improved by oat hull inclusion. 3. Gizzard size increased with inclusion of oat hulls, whole wheat, wood shavings and grit. 4. Starch digestibility was significantly increased by inclusion of oat hulls for broilers, and by wood shavings for layers. 5. Wood shavings and whole wheat did not affect bile acid concentration of gizzard contents. However, the total amount of bile acids in gizzard increased with access to wood shavings due to an increase in the weight of gizzard contents, indicating an increased gastroduodenal reflux. 6. Fibre concentration was considerably higher in the gizzard contents than in the feed. 7. Duodenal particle size decreased with access to grit. No effect of hulls or whole wheat inclusion was found, indicating that all particles are ground to a certain critical size before leaving the gizzard.

This article investigates whether forest certification (eco-labeling) is likely to rectify certain omissions in the current global forest regime. Following an examination of the achievements and shortcomings of the forest regime to date, I argue that gaps could be filled by including a broad range of stakeholders in certification standards development; promoting strong environmental and social performance standards in forestry; providing effective control mechanisms; securing producer participation; and penetrating markets. Although the Forest Stewardship Council (FSC) was considered initially to have the greatest potential to fill these gaps, the emergence and widespread proliferation of industry-dominated schemes have marginalized the FSC in many countries. The study shows that while forest certification would probably promote more sustainable forestry in the temperate and boreal zones than it would in the tropical zone, the ability of this tool to actually do so remains to be seen.

The aim of the present study was to evaluate the importance of social status and lifestyle for dietary habits, since these factors may influence life expectancy. We studied the association of four indicators for healthy dietary habits (fruits and vegetables, fibre, fat and Hegsted score) with sex, age, socio-economic status, education, physical leisure exercise, smoking and personal attention paid to keeping a healthy diet. Data were gathered with a self-administered quantitative food-frequency questionnaire distributed to a representative sample of Norwegian men and women aged 16-79 years in a national dietary survey, of whom 3144 subjects (63%) responded. Age and female sex were positively associated with indicators for healthy dietary habits. By separate evaluation length of education, regular physical leisure exercise and degree of attention paid to keeping a healthy diet were positively associated with all four indicators for healthy dietary habits in both sexes. Socio-economic status, location of residence and smoking habits were associated with from one to three indicators for healthy dietary habits. In a multiple regression model, age, education and location of residence together explained from 1 to 9% of the variation (R2) in the four dietary indicators. Length of education was significantly associated with three of four dietary indicators both among men and women. By including the variable 'attention paid to keeping a healthy diet' in the model, R2 increased to between 4 and 15% for the four dietary indicators. Length of education remained correlated to three dietary indicators among women, and one indicator among men, after adjusting for attention to healthy diet, age and location of residence. Residence in cities remained correlated to two indicators among men, but none among women, after adjusting for age, education and attention to healthy diet. In conclusion, education was associated with indicators of a healthy diet. Attention to healthy diet showed the strongest and most consistent association with all four indicators for healthy dietary habits in both sexes. This suggests that personal preferences may be just as important for having a healthy diet as social status determinants.