University Museum Utrecht

The sperm whale (<em>Physeter</em> <em>macrocephalus</em>, Linnaeus 1758) possesses the largest brain that ever existed. Relatively few authors have dealt with it and the available descriptions are heterogeneous, with only few data about brain weight or gross anatomy. In fact the central nervous system of large cetaceans is quite difficult to obtain, given the huge body size and the low frequency of strandings of recently dead individuals. Furthermore, since the skull of the sperm whale underwent an extreme transformation for the accommodation of the spermaceti organ, the cranial cavity is surrounded by thick layers of bone and thus difficult to reach under field conditions. We recently had the chance to extract the brain from two stranded sperm whales whose bodies were in good condition. In the present note we describe the main macroscopic characteristics of the sperm whale brain, including its weight and Encephalization Quotient, review the available literature, and describe a possible new approach to the removal and preservation of the organ under field conditions.

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ETHNOPHARMACOLOGICAL RELEVANCE: The Westhoff collection of Chinese materia medica (c. 1870) at the Utrecht University Museum in Utrecht, the Netherlands, contains an original, handwritten catalogue, which was putatively ascribed to a Chinese medicine practitioner. It provides a detailed record of the Chinese names, plant parts, preparations, and applications of the specimens contained in glass bottles, which probably reflects the physician's personal interpretation of Chinese medicine in Indonesia at the end of the 19th century. Such individual catalogues can reveal historical changes and regional variations in the use of traditional Chinese medicine, which can lead to a better understanding of the history and development of this field. AIM OF THE STUDY: We addressed the following questions: 1) What are the contents of the Westhoff catalogue? 2) What medicinal preparations and applications were recorded in the catalogue, and which ones are dominant? 3) How similar is the use of Chinese materia medica in Westhoff catalogue compared to the modern Chinese Pharmacopeia? 4) What other specific information is contained in the Westhoff catalogue? MATERIALS AND METHODS: The catalogue had been digitized previously, and all handwritten Dutch text has been transcribed and translated into English. The information for each entry was summarized and analyzed, the medicinal applications were compared to modern Chinese pharmacopeia or other monographs on Chinese materia medica. RESULTS: The catalogue contains 436 entries, for which 395 corresponding specimens still exist in the Westhoff collection of Chinese materia medica. Each entry contains a serial number, a Chinese name, a phonetic Dutch transcription of the Chinese name, a description of the plant, animal, or mineral origin of the medicinal product, the preparation method, and the medical indication for which it should be used. The dominant preparation method is decoction (79% of the entries). The most frequently mentioned applications are fever, skin diseases, strengthening and wounds. Around 80% of the medicinal applications in the catalogue were also listed for the same CMM in modern monographs. The catalogue also sheds light on typical characteristics of popular medicine, their geographic origin, and social aspects of traditional Chinese medicine in Indonesia around 1870. CONCLUSIONS: The Westhoff catalogue is a valuable record of Chinese materia medica and its practice in a specific time and space. It reflects an individual physician's interpretation of Chinese medicine, shows the difficulties in the interpretation of cultural-bound health issues between the Dutch and the Chinese, and provides evidence that traditional Chinese medicine spread not only in East Asia but also to the distant Western world.

Where the ever-rolling waves of the ocean throw their white foam on to the coast of France and change colour as the weather changes, Jules Verne was born. Where sailors and fishermen returned with their merchandise and strange creatures of the sea, the boy grew up. Dreaming of strange and far-away countries, he spent his free hours at the harbour in his birthplace Nantes. Perhaps it was in these early days in the second quarter of the nineteenth century that the foundation was laid for the ideas realised in the numerous books he wrote later. Books which were called by many a biographist fantastic, or, what is more, prophetic. See, wrote some biographers, how Jules Verne saw things which did not exist in his day. The tendency to exaggerate the prophetic qualities of the well-known author is increasing in this day of spaceflight and atomic submarines.