University of North Carolina School of the Arts

This article introduces the Inventory of Creative Activities and Achievements (ICAA), a broad-based assessment of individual differences in real-life creativity. The ICAA provides independent scales for the frequency of engagement in everyday creative activity and the level of creative achievement across 8 creative domains. A formal test analysis based on 7 Little-C samples and 2 Pro-C samples (overall N = 1,566) provides evidence for the reliability and validity of the ICAA test scores. The analyses shed light on the prevalence of specific creative activity and achievement and examine the relevance of personality, creative potential, and intelligence across domains of creativity. The findings further suggest that the assessment of creative activity is particularly suited for Little-C creativity, whereas the assessment of creative achievement appears more appropriate for Pro-C creativity. The ICAA offers researchers a broad and versatile assessment tool for studying creativity across domains and levels.

In this introduction to the special issue Representing Trans, the authors reflect on the radical changes in trans representation between the early 1990s and the present. Through brief reflections on Pose (2018-) and other landmark examples of trans representation in film and television, the authors show how these changes attest to complex interrelations between visibility, recognition, and violence. Beyond the realm of film and television, the introduction also discusses broader media representations that connect the question of visibility to political debates and the regulation of public spaces. Highlighting a variety of trans theorical engagements with different forms of mediality (including literature), the authors propose a more expansive understanding of trans as a reading practice as well as a method of analysing and transing medial forms.

We have previously demonstrated the immunogenicity of VGX-3100, a multicomponent DNA immunotherapy for the treatment of Human Papillomavirus (HPV)16/18-positive CIN2/3 in a phase 1 clinical trial. Here, we report on the ability to boost immune responses with an additional dose of VGX-3100. Patients completing our initial phase 1 trial were offered enrollment into a follow on trial consisting of a single boost dose of VGX-3100. Data show both cellular and humoral immune responses could be augmented above pre-boost levels, including the induction of interferon (IFN)γ production, tumor necrosis factor (TNF)α production, CD8+ T cell activation and the synthesis of lytic proteins. Moreover, observation of antigen-specific regulation of immune-related gene transcripts suggests the induction of a proinflammatory response following the boost. Analysis of T cell receptor (TCR) sequencing suggests the localization of putative HPV-specific T cell clones to the cervical mucosa, which underscores the putative mechanism of action of lesion regression and HPV16/18 elimination noted in our double-blind placebo-controlled phase 2B trial. Taken together, these data indicate that VGX-3100 drives the induction of robust cellular and humoral immune responses that can be augmented by a fourth “booster” dose. These data could be important in the scope of increasing the clinical efficacy rate of VGX-3100. We have previously demonstrated the immunogenicity of VGX-3100, a multicomponent DNA immunotherapy for the treatment of Human Papillomavirus (HPV)16/18-positive CIN2/3 in a phase 1 clinical trial. Here, we report on the ability to boost immune responses with an additional dose of VGX-3100. Patients completing our initial phase 1 trial were offered enrollment into a follow on trial consisting of a single boost dose of VGX-3100. Data show both cellular and humoral immune responses could be augmented above pre-boost levels, including the induction of interferon (IFN)γ production, tumor necrosis factor (TNF)α production, CD8+ T cell activation and the synthesis of lytic proteins. Moreover, observation of antigen-specific regulation of immune-related gene transcripts suggests the induction of a proinflammatory response following the boost. Analysis of T cell receptor (TCR) sequencing suggests the localization of putative HPV-specific T cell clones to the cervical mucosa, which underscores the putative mechanism of action of lesion regression and HPV16/18 elimination noted in our double-blind placebo-controlled phase 2B trial. Taken together, these data indicate that VGX-3100 drives the induction of robust cellular and humoral immune responses that can be augmented by a fourth “booster” dose. These data could be important in the scope of increasing the clinical efficacy rate of VGX-3100.

College access for undocumented students in the United States continues to be a politically contested issue in many states across the country. Whereas a growing number have created friendly admission policies, such as in-state tuition benefits, other states—like Georgia—impose restrictive guidelines that work to reduce the number of undocumented students enrolling in public higher education. Through analyzing 26 participant interviews, this study examined how Freedom University, a nonprofit organization, worked to help students further their dream of earning a college degree by creating a college-going climate and sharing social and cultural capital to educate students about their postsecondary opportunities.

In this consensual qualitative research study, the authors explored supervisors' ( n = 11) and their supervisees' ( n = 31) perceptions of individual, triadic, and group supervision sessions during practicum. Data from supervisor individual interviews and supervisee focus‐group interviews revealed several themes regarding the advantages and disadvantages of each supervision modality. Findings suggest the relative place of each modality in terms of goals and impact.

Abstract In the shadows of a Shinto torii (gateway) in São Paulo's ‘Japanese’ neighbourhood rests the city's first burial ground for enslaved Africans. Recently unearthed, the gravesite is one of the few visible remains of the Liberdade neighbourhood's significance in São Paulo's ‘Black zone’. This article excavates the history of the nearby Remedies church, the headquarters of Brazil's Underground Railroad and a long-time museum to the enslaved. The 1942 demolition of the Remedies church, I argue, comprised part of a spatial project of forgetting centred on razing the city's ‘Black zone’ and reproducing São Paulo as a non-Black, ethnically immigrant metropolis.

Filmmakers use various cinematic techniques in an effort to guide attention to certain aspects of these events. The present study was conducted to investigate how framing and editing can guide viewers’ attention toward character actions during event segmentation. Participants watched and segmented a movie that simultaneously showed two actors engaged in two related activities. Participants watched one of three versions of the movie: Static center version that did not foreground any character; Static off-center version that foregrounding one of the characters, and an edited version with a mix of shots that foregrounding both characters. Participants engaged in an event partonomy task in which they were asked to identify the boundaries between the events that were depicted in the movie. After watching the movie, they were asked to recall the events. The results showed converging evidence between the event segmentation and recall data, which both indicated that cinematic devices affect the perception and memory of the event structure depicted in the film.

This article presents new approaches for investigating the past using digital technologies. "Pauliceia 2.0: collaborative mapping of the history of São Paulo (1870-1920)" is an open-source project intended to broadly engage with the public through collaborative methodologies. This text discusses the concept, current status, and prospects of this project, and presents it as a case study to discuss the relationship between digital technologies and historical methods. The product of this journey (at least the outcome intended by the authors and the other team members listed at the end of the article) is meant to assign new meaning to the project at the juncture between digital humanities, public history, and open science.

Counselor mindfulness practice may help cultivate common therapeutic factors (e.g., empathy, working alliance). Researchers in this quantitative research study identified significant relationships between therapist mindfulness and client perceptions of the therapist's way of being and the working alliance. The impact of meditation training on these variables was also explored.

A number of literature reviews exist that support the use of psychotropic medications. This article provides a review of the disconfirming literature regarding psychopharmacology use. Comparing the first review of psychopharmacology published in the counseling field two decades earlier to what is known currently, I examine recent developments in psychopharmacology research focusing on the safety, efficacy, side-effects, and theoretical assumptions of various classes of psychotropic medications. This article concludes by addressing counselor identity, practice and training concerns vis-à-vis psychiatric medications and the medical model.

ABSTRACT Chick cells in primary culture synthesize protein at an accelerated rate following recovery from prolonged (2‐12 hr) inhibition of protein synthesis. This ‘overshoot’ is followed by a return to the normal rate of synthesis. Both actinomycin and fluorophenylalanine provided during the recovery period enhance the ‘overshoot’ and prevent the return to normal. The results are consistent with the proposal that protein synthesis is restricted by an inhibitor or ‘governor’, itself a protein of relatively short half life. Neither L nor HeLa cells demonstrate an ‘overshoot’ during the recovery phase.

Electrical Impedance Spectroscopy (EIS) is a non-invasive and label-free technology that can characterize and discriminate cells based on their dielectric properties at a wide range of frequency. This characterization method has not been utilized for small extracellular vesicles (exosomes) with heterogenous and nano-scale size distribution. Here, we developed a novel label-free microelectronic impedance spectroscopy for non-invasive and rapid characterization of exosomes based on their unique dielectric properties. The device is comprised of an insulator-based dielectrophoretic (iDEP) module for exosomes isolation followed by an impedance spectroscopy utilizing the embedded micro-electrodes. This device is capable of distinguishing between exosomes harvested from different cellular origins as the result of their unique membrane and cytosolic compositions at a wide range of frequency. Therefore, it has the potential to be further evolved as a rapid tool for characterization of pathogenic exosomes in clinical settings.

The psychopharmaceutical industrial complex (PPIC) and its adherence to the disease model pervades mainstream culture and greatly impacts psychotherapy. Consequently, the effects of the PPIC may have resulted in some psychiatric consumers adopting disease-model messages in ways similar to cult indoctrination. Consumer adoption of the disease model can create obstacles to treatment when hope is fundamental. In this article, I draw parallels between cult indoctrination and PPIC techniques and note similarities between cult members and consumers who are vulnerable to losing their identities to the PPIC. Suggestions for the profession of mental health counseling and those working with these consumers conclude the article.

Familial hemophagocytic lymphohistiocytosis is a rare and inherited disease that affects both males and females equally and is most often fatal if not treated. Diagnosis is challenging because it mimics severe sepsis by demonstrating hepatomegaly, splenomegaly, persistent fever, central nervous system involvement, and cytopenias. The etiologies of hemophagocytic lymphohistiocytosis have been well established through the identification of 3 causative genetic mutations. Therapies for hemophagocytic lymphohistiocytosis focus on restoring health by diminishing the disease sequelae with a goal of hematopoietic stem cell transplant, the only known curative therapy for hemophagocytic lymphohistiocytosis. Current research is being conducted to identify other causative genetic mutations and newer, more effective treatment modalities.

Abstract The primary purpose of this study was to develop an alternative model, the Prelaboratory Preparation Period (PLPP), to be used to introduce freshman level students to weekly laboratories and to evaluate student academic achievement as the result of attending the Prelaboratory Preparation Period. The sample was composed of 233 students taking introductory chemistry at Auburn University. The data were collected over a four quarter period of time. A posttest‐only control group design with five experimental and three control groups was used to investigate the effect of the Prelaboratory Preparation Period. A Multivariate Analysis of Variance (MANOVA) was used to determine if significant differences existed between academic achievement of the experimental and control groups. Results of the analysis indicated that a significant difference (α = 0.05) in academic performance existed between the two groups. It was concluded that the Prelaboratory Preparation Period increased the academic achievement of students enrolled in an introductory chemistry course.

The hypothesis that students who are characterized as having external versus internal control would achieve differently under different classroom instructional treatments was tested. Thirty-two seventh-grade boys (sixteen externals and sixteen internals) were randomly assigned to two instructional treatments in science. The treatments varied according to the amount of control exercised by the teacher. The role-assumption treatment emphasized student-directed learning experiences, whereas the structured treatment had maximum teacher control. The treatments were applied for 16 weeks. Analysis of covariance confirmed the hypothesis. The significant interaction indicated that internals achieved at the same level under both treatments, whereas externals achieved more under the role-assumption treatment.

Since the implementation of Common Core, my dance classes have have become a lot noisier, and I am losing control. That is a good thing.As a dance teacher in public elementary schools for the last ...

Abstract Filmmakers must rely on cinematic devices of perspective (close-ups and point-of-view shot sequencing) to emphasize facial expressions associated with affective states. This study explored the extent to which differences in the use of these devices across two films that have the same content lead to differences in the understanding of the affective states of characters. Participants viewed one of two versions of the films and made affective judgments about how characters felt about one another with respect to saddness and anger. The extent to which the auditory and visual contexts were present when making the judgments was varied across four experiments. The results of the study showed judgments about sadness differed across the two films, but only when the entire context (sound and visual input) were present. The results are discussed in the context of the role of facial expressions and context in inferring basic emotions.

This paper reports on an NSF-grant supported summer workshop that brought music and computer science students together for eight weeks to explore creative projects in digital sound production. The dynamics of the students' collaborations were observed as they crafted experimental projects weaving together music, theatre production, sampled digital audio, and MIDI. Moving among various levels of abstraction, the students found practical and artistic motivations to learn the science of digital sound. The projects they produced suggest ways to revitalize computer science courses by linking science, art, and practice through digital sound, a subject naturally interesting to students.

The rise of students seeking entry into nursing programs and the barriers that have challenged clinical placement has forced nursing programs to use alternate clinical experiences. Virtual reality is a newer technological advancement that serves as an alternate clinical experience. A four-step development process created a three (3) part VR clinical scenario. VR is quickly emerging, and although not extensively used in nursing education, educators can benefit from implementing it as an alternate clinical experience.