Effect of 12 mg vs 6 mg of Dexamethasone on the Number of Days Alive Without Life Support in Adults With COVID-19 and Severe Hypoxemia: The COVID STEROID 2 Randomized Trial.

W. Munch, M.; Myatra, S.; Vijayaraghavan, B.; Saseedharan, S.; Benfield, T.; R. Wahlin, R.; Rasmussen, B.; S. Andreasen, A.; M. Poulsen, Lone; Cioccari, L.; Khan, M.; Kapadia, F.; Divatia, J.; C. Brøchner, A.; Bestle, M.; Helleberg, M.; Michelsen, J.; Padmanaban, Ajay; Bose, N.; Møller, A.; Borawake, K.; T. Kristiansen, K.; Shukla, U.; Chew, M.; Dixit, S.; Ulrik, C.; Amin, P.; Chawla, R.; Wamberg, C.; Shah, Mehul; S. Darfelt, I.; Jørgensen, V.; Smitt, M.; Granholm, A.; N. Kjær, M.; Møller, M.; Meyhoff, T.; K. Vesterlund, G.; Hammond, N.; Micallef, S.; Bassi, Abhinav; John, Oommen; Jha, Anubhuti; Cronhjort, M.; Jakob, S.; Gluud, C.; Lange, T.; Kadam, Vaijayanti; V. Marcussen, Klaus; Hollenberg, J.; Hedman, A.; Nielsen, H.; Schjørring, O.; Q. Jensen, M.; W. Leistner, J.; Jonassen, T.; M. Kristensen, C.; C. Clapp, Esben; J. Hjortsø, C.; S. Jensen, T.; S. Halstad, Liv; R. B. Bak, Emilie; Zaabalawi, Reem; Metcalf-Clausen, Matias; Abdi, Suhayb; Hatley, E.; S. Aksnes, Tobias; Gleipner-Andersen, Emil; F. Alarcón, Arif; Yamin, Gabriel; Heymowski, Adam; Berggren, Andreas; N la Cour, Kirstine; Weihe, Sarah; H. Pind, A.; Engstrøm, Janus; Jha, V.; Venkatesh, B.; Perner, A.

doi:10.1001/jama.2021.18295

Public

Effect of 12 mg vs 6 mg of Dexamethasone on the Number of Days Alive Without Life Support in Adults With COVID-19 and Severe Hypoxemia: The COVID STEROID 2 Randomized Trial.

Shared by NobleBlocks on Oct 21, 2021 • 12:00 AM UTC

Authors:

M. W. Munch

S. Myatra

B. Vijayaraghavan

Abstract

Importance A daily dose with 6 mg of dexamethasone is recommended for up to 10 days in patients with severe and critical COVID-19, but a higher dose may benefit those with more severe disease. Objective To assess the effects of 12 mg/d vs 6 mg/d of dexamethasone in patients with COVID-19 and severe ...

Subject

Medicine

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