Reduction of adverse effects from intravenous acetylcysteine treatment for paracetamol poisoning: a randomised controlled trial.

Nicholas Bateman, D; W Dear, James; K Ruben Thanacoody, H; H L Thomas, Simon; Eddleston, Michael; A Sandilands, Euan; Coyle, Judy; G Cooper, Jamie; Rodriguez, Aryelly; Butcher, Isabella; C Lewis, Steff; D Bastiaan Vliegenthart, A; Veiraiah, Aravindan; J Webb, David; Gray, Alasdair

doi:10.1016/S0140-6736(13)62062-0

Public

Reduction of adverse effects from intravenous acetylcysteine treatment for paracetamol poisoning: a randomised controlled trial.

Shared by NobleBlocks on Feb 22, 2014 • 12:00 AM UTC

Authors:

D Nicholas Bateman

James W Dear

H K Ruben Thanacoody

Abstract

BACKGROUND: Paracetamol poisoning is common worldwide. It is treated with intravenous acetylcysteine, but the standard regimen is complex and associated with frequent adverse effects related to concentration, which can cause treatment interruption. We aimed to ascertain whether adverse effects could...

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