Comprehensive genomic characterization of squamous cell lung cancers

Hammerman, P.; Voet, D.; Lawrence, M.; Voet, D.; Jing, R.; Cibulskis, K.; Sivachenko, A.; Stojanov, P.; McKenna, A.; Lander, E.; Gabriel, S.; Getz, G.; Imieliński, M.; Helman, E.; Hernandez, Bryan; Pho, Nam; Meyerson, M.; Chu, Andy; E. Hye-Chun, Jung; Mungall, A.; Pleasance, E.; G. Robertson, A.; Sipahimalani, Payal; Stoll, D.; Balasundaram, M.; Birol, I.; Butterfield, Y.; Chuah, E.; Coope, R.; Corbett, R.; Dhalla, Noreen; Guin, R.; He, A.; Hirst, Carrie; Hirst, M.; Holt, R.; Lee, Darlene; Li, H.; Mayo, Michael; A. Moore, Richard; Mungall, K.; Nip, K.; Olshen, A.; Schein, J.; R. Slobodan, Jared; Tam, Angela; Thiessen, N.; Varhol, R.; Zeng, Thomas; Zhao, Yongjun; J. M. Jones, Steven; Marra, M.; Saksena, G.; Cherniack, A.; Schumacher, S.; Tabak, B.; Carter, S.; L. Nguyen, Huy; Onofrio, R.; Crenshaw, A.; Ardlie, K.; Beroukhim, R.; Winckler, W.; Protopopov, A.; Zhang, Jianhua; Hadjipanayis, Angela; Lee, Semin; Xi, Ruibin; Yang, Lixing; Ren, X.; Zhang, Hailei; Shukla, S.; Chen, Peng-Chieh; S. Haseley, Psalm; Lee, E.; Chin, L.; Park, P.; Kucherlapati, R.; Socci, N.; Liang, Yupu; Schultz, N.; Borsu, L.; Lash, A.; Viale, A.; Sander, C.; Ladanyi, M.; Auman, J.; Hoadley, K.; Wilkerson, M.; Shi, Yan; Liquori, C.; Meng, S.; Li, Ling; J. Turman, Yidi; D. Topal, M.; Tan, Donghui; Waring, S.; Buda, Elizabeth; L. Walsh, Jesse; D. Jones, Corbin; Mieczkowski, P.; Singh, Darshan; Wu, Junyuan; Gulabani, Anisha; Dolina, Peter; Bodenheimer, T.; Hoyle, A.; Simons, J.; G. Soloway, Matthew; M. Stuart, Joshua; E. Mose, Lisle; Jefferys, S.; Balu, S.; O’Connor, Brian; Y. Chiang, Derek; Liu, Jinze; Hayes, D.; Perou, C.; M. Cope, Leslie; Weisenberger, D.; V. Danilova, Ludmila; Weisenberger, D.; Maglinte, D.; Pan, F.; V. Berg, D.; Triche, T.; Herman, J.; Baylin, S.; Laird, P.; Noble, M.; Gehlenborg, Nils; Dicara, D.; Zhang, Jinhua; Wu, Chang-Jiun; Y. Liu, S.; Zou, L.; Lin, Pei; Cho, Juok; Nazaire, Marc-Danie; Robinson, James; Thorvaldsdóttir, H.; Mesirov, J.; Sinha, Rileen; Ciriello, G.; Cerami, E.; E. Gross, Benjamin; Jacobsen, A.; Gao, Jianjiong; A. Aksoy, B.; Weinhold, Nils; Ramirez, Ricardo; Taylor, B.; Antipin, Y.; Reva, B.; Mo, Q.; Seshan, V.; Paik, P.; Akbani, Rehan; Zhang, Nianxiang; Broom, B.; D. Casasent, Tod; Unruh, A.; Wakefield, Chris; Cason, R.; Baggerly, K.; Weinstein, J.; Haussler, D.; Benz, C.; Zhu, Jingchun; Szeto, C.; Scott, G.; Yau, C.; Ng, S.; Goldstein, Theodore; Waltman, Peter; Sokolov, A.; Collisson, E.; Ellrott, K.; Zerbino, D.; Ma, Singer; Craft, B.; Du, Ying; R. Cabanski, Christopher; Walter, Vonn; Marron, J.; Liu, Yufeng; Wang, Kai; Prins, J.; Creighton, C.; Zhang, Yiqun; Travis, W.; Rekhtman, N.; E. Yi, Joanne; Aubry, M.; Cheney, R.; Dacic, S.; Flieder, D.; Funkhouser, W.; Illei, P.; Myers, J.; Tsao, M.; Penny, R.; Mallery, D.; Shelton, T.; Hatfield, M.; Morris, S.; Yena, P.; Shelton, C.; Sherman, M.; Paulauskis, J.; Govindan, R.; Azodo, I.; Beer, D.; Bose, R.; Byers, L.; Carbone, D.; Chang, Li-Wei; Chun, Elizabeth; Ding, L.; Heymach, J.; Ida, C.; Johnson, B.; Jurisica, I.; Kaufman, J.; Kosari, F.; Kwiatkowski, D.; Maher, C.; Mungall, A.; Pao, W.; Peifer, M.; Robertson, Gordon; Rusch, V.; Siegfried, J.; Sougnez, C.; K. Thomas, Roman; Tomaszek, S.; J. Vaske, Charles; Wheeler, D.; Wigle, D.; Wilks, C.; Zhang, Jianjuan; Jensen, M.; Sfeir, R.; Kahn, A.; Chu, A.; Kothiyal, Prachi; Wang, Zhining; Snyder, E.; Pontius, J.; Pihl, T.; Ayala, Brenda; Backus, M.; L Walton, Jessica; Baboud, J.; Berton, D.; Nicholls, M.; Srinivasan, D.; Raman, R.; Girshik, Stanley; A. Kigonya, Peter; Alonso, S.; N. Sanbhadti, Rashmi; Barletta, S.; Greene, J.; Pot, D.; Bandarchi-Chamkhaleh, B.; Boyd, J.; Weaver, J.; Azodo, I.; Ida, C.; Yang, Ping; Brock, M.; Rogers, K.; Rutledge, M.; Brown, T.; Lee, Beverly; Shin, James; Trusty, D.; Dhir, R.; Potapova, O.; Fedosenko, K.; Nemirovich-Danchenko, E.; Zakowski, M.; Iacocca, M.; Brown, Jennifer; Rabeno, B.; Czerwinski, Christine; Petrelli, N.; Fan, Zhen; Todaro, N.; Eckman, J.; Rathmell, W.; Thorne, L.; Huang, Meijuan; Boice, L.; D. Hill, Ashley; E. Curley, Erin; Morrison, C.; Gaudioso, Carmelo; Bartlett, J.; Kodeeswaran, S.; Zanke, B.; Sekhon, H.; David, K.; Juhl, H.; Le, X.; Kohl, B.; A. Thorp, Richard; Tien, N.; V. Bằng, N.; Sussman, H.; Duc Phu, Bui; Hajek, R.; P. Hung, N.; Z. Khan, K.; Muley, T.; Shaw, K.; Sheth, Margi; Yang, Liming; Buetow, K.; Davidsen, Tanja; Demchok, J.; Eley, G.; Ferguson, M.; A. L. Dillon, Laura; Schaefer, C.; Guyer, M.; Ozenberger, B.; D. Palchik, Jacqueline; L. Peterson, Jane; Sofia, H.; Thomson, E.; Shen, R.

doi:10.1038/nature11404

Public

Comprehensive genomic characterization of squamous cell lung cancers

Shared by NobleBlocks on Sep 9, 2012 • 12:00 AM UTC

Authors:

P. Hammerman

D. Voet

M. Lawrence

Abstract

Lung squamous cell carcinoma is a common type of lung cancer, causing approximately 400,000 deaths per year worldwide. Genomic alterations in squamous cell lung cancers have not been comprehensively characterized, and no molecularly targeted agents have been specifically developed for its treatment....

Subject

Medicine

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