Lung adenocarcinoma promotion by air pollutants

Hill, William; L. Lim, Emilia; Weeden, C.; Lee, Claudia; Augustine, M.; Chen, Kezhong; Kuan, F.; Marongiu, F.; J. Evans, E.; Moore, D.; S. Rodrigues, F.; Pich, O.; Bakker, B.; Cha, H.; Myers, R.; van Maldegem, F.; Boumelha, J.; Veeriah, S.; Rowan, A.; Naceur-Lombardelli, C.; Karasaki, T.; Sivakumar, Monica; De, Swapnanil; Caswell, D.; Nagano, Ai; R. M. Black, James; Martínez-Ruiz, Carlos; Ryu, M.; D. Huff, Ryan; Li, Shijian; Favé, M.; Magness, Alastair; Suárez‐Bonnet, A.; Priestnall, S.; Lüchtenborg, M.; Lavelle, K.; Pethick, Joanna; I Hardy, Steven; McRonald, F.; Lin, Meng-Hung; I. Troccoli, Clara; Ghosh, Moumita; Miller, Y.; Merrick, D.; Keith, R.; Al Bakir, M.; Bailey, Chris; Hill, M.; Saal, L.; Chen, Yilun; George, A.; Abbosh, C.; Kanu, N.; Lee, Se-Hoon; Mcgranahan, N.; Berg, C.; Sasieni, P.; Houlston, R.; Turnbull, C.; Lam, Stephen; Awadalla, P.; Grönroos, E.; Downward, J.; Jacks, T.; Carlsten, C.; Malanchi, I.; Hackshaw, A.; Litchfield, K.; F. Amrita Apostolos Azmina Keng Mohamad Mohammed F Lester Bajaj Nakas Sodha-Ramdeen Ang Tufail Chowdh, Jason; Lester, Jason; Bajaj, A.; Nakas, A.; Sodha-Ramdeen, Azmina; Ang, K.; Tufail, M.; F. Chowdhry, M.; Scotland, M.; Boyles, R.; Rathinam, S.; Wilson, Claire; Marrone, Domenic; Dulloo, S.; Fennell, D.; Matharu, Gurdeep; Shaw, J.; Riley, Joan; Primrose, L.; Boleti, E.; Cheyne, Heather; Khalil, Mohammed; Richardson, S.; Cruickshank, Tracey; Price, Gillian; Kerr, K.; Benafif, S.; Gilbert, Kayleigh; Naidu, B.; J. Patel, Akshay; Osman, A.; Lacson, Christer; Langman, G.; Shackleford, Helen; Djearaman, M.; Kadiri, S.; Middleton, Gary; E. Leek, Angela; Davies Hodgkinson, Jack; Totten, Nicola; Montero, A.; Smith, E.; Fontaine, E.; Granato, F.; Doran, H.; Novasio, Juliette; Rammohan, K.; Joseph, L.; Bishop, P.; Shah, R.; Moss, Stuart; Joshi, Vijay; Crosbie, P.; Gomes, F.; Brown, Kate; Carter, M.; Chaturvedi, A.; Priest, L.; Oliveira, P.; Lindsay, C.; Blackhall, F.; Krebs, M.; Summers, Y.; Clipson, A.; Tugwood, J.; Kerr, Alastair; Rothwell, D.; Kilgour, E.; Dive, C.; Aerts, H.; Schwarz, R.; L. Kaufmann, Tom; Wilson, G.; Rosenthal, R.; van Loo, P.; J. Birkbak, Nicolai; Szallasi, Z.; Kisistók, Judit; Sokač, M.; Salgado, Roberto; Dióssy, M.; Demeulemeester, J.; Bunkum, Abigail; Stewart, A.; Frankell, A.; Karamani, A.; Toncheva, A.; Huebner, A.; Chain, B.; Campbell, B.; Castignani, Carla; Puttick, C.; Richard, Corentin; Hiley, C.; Pearce, D.; Karagianni, D.; Biswas, D.; Levi, D.; Hoxha, Elena; L. Cadieux, E.; Colliver, E.; Nye, E.; Gálvez-Cancino, F.; Athanasopoulou, Foteini; Gimeno-Valiente, F.; Kassiotis, G.; Stavrou, Georgia; Mastrokalos, Gerasimos; Zhai, Haoran; Lowe, H.; Matos, Ignacio; Goldman, J.; Reading, J.; Herrero, Javier; Rane, J.; Nicod, J.; Lam, J.; Hartley, J.; Peggs, K.; S. S. Enfield, Katey; Selvaraju, Kayalvizhi; Thol, K.; Ng, K.; Dijkstra, K.; Grigoriadis, Kristiana; Thakkar, K.; Ensell, L.; Shah, Mansi; Durán, Mar; Litovchenko, Maria; W. Sunderland, M.; Dietzen, M.; M. Leung, Michelle; Escudero, M.; Angelova, M.; Tanić, M.; Chervova, O.; Lucas, O.; Al-Sawaf, O.; Prymas, Paulina; Hobson, P.; Pawlik, Piotr; Stone, R.; Bentham, R.; Hynds, R.; Vendramin, R.; Saghafinia, S.; López, Saioa; Gamble, Samuel; Ung, S.; Quezada, S.; Vanloo, S.; Zaccaria, Simone; Hessey, S.; Ward, S.; Boeing, S.; Beck, Stephan; Bola, S.; Denner, Tamara; Marafioti, T.; P. Mourikis, Thanos; Watkins, T.; Spanswick, V.; Barbè, Vittorio; Lu, Wei-Ting; Liu, Wing-Kin; Wu, Yin; Naito, Yutaka; Ramsden, Z.; Veiga, C.; Royle, G.; Collins-Fekete, C.; Fraioli, F.; Ashford, P.; Clark, T.; D. Forster, Martin; Lee, Siow-Ming; Borg, E.; Falzon, M.; Papadatos-Pastos, D.; Wilson, James; Ahmad, T.; Procter, A.; Ahmed, Asia; N. Taylor, Magali; Nair, A.; Lawrence, D.; Patrini, D.; Navani, N.; Thakrar, R.; Janes, S.; M. Hoogenboom, E.; Monk, Fleur; W. Holding, James; Choudhary, Junaid; Bhakhri, Kunal; Scarci, M.; Hayward, M.; Panagiotopoulos, N.; Gorman, Pat; Khiroya, R.; Stephens, R.; Wong, Y.; Bandula, S.; Sharp, A.; Smith, Sean; Gower, N.; Dhanda, H.; Chan, Kitty; Pilotti, Camilla; Leslie, R.; Grapa, Anca-Ioana; Zhang, Hanyun; AbdulJabbar, K.; Pan, Xiaoxi; Yuan, Yinyin; Chuter, D.; Mackenzie, M.; Chee, S.; Alzetani, A.; Cave, J.; Scarlett, Lydia; Richards, J.; Ingram, Papawadee; Austin, S.; Lim, Eric; De Sousa, P.; Jordan, S.; Rice, A.; Raubenheimer, H.; Bhayani, H.; Ambrose, L.; Devaraj, A.; Chavan, Hema; Begum, S.; Buderi, S.; Kaniu, Daniel; Malima, Mpho; Booth, S.; Nicholson, A.; Fernandes, Nádia; Shah, P.; Proli, C.; Hewish, M.; Danson, S.; Shackcloth, M.; Robinson, Lily; Russell, P.; Blyth, K.; Dick, C.; Le Quesne, J.; Kirk, A.; Asif, M.; Bilancia, R.; Kostoulas, N.; Thomas, Mathew; DeGregori, J.; Jamal-Hanjani, M.; Swanton, C.

doi:10.1038/s41586-023-05874-3

Public

Lung adenocarcinoma promotion by air pollutants

Shared by NobleBlocks on Apr 1, 2023 • 12:00 AM UTC

Authors:

William Hill

Emilia L. Lim

C. Weeden

Abstract

A complete understanding of how exposure to environmental substances promotes cancer formation is lacking. More than 70 years ago, tumorigenesis was proposed to occur in a two-step process: an initiating step that induces mutations in healthy cells, followed by a promoter step that triggers cancer d...

Subject

Medicine

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