Adjuvant Trastuzumab in HER2-Positive Breast Cancer

Slamon, D.; Eiermann, W.; Robert, N.; Pieńkowski, T.; Martín, Miguel; Press, M.; Mackey, J.; Glaspy, J.; Chan, A.; Pawlicki, M.; Pintér, T.; Valero, V.; Liu, Mei-Ching; Sauter, G.; von Minckwitz, G.; Visco, F.; Bée, V.; Buyse, M.; Bendahmane, B.; Tabah-Fisch, I.; Lindsay, M.; Riva, A.; Crown, J.

doi:10.1056/NEJMoa0910383

Public

Adjuvant Trastuzumab in HER2-Positive Breast Cancer

Shared by NobleBlocks on Oct 5, 2011 • 12:00 AM UTC

Authors:

D. Slamon

W. Eiermann

N. Robert

Abstract

BACKGROUND Trastuzumab improves survival in the adjuvant treatment of HER-positive breast cancer, although combined therapy with anthracycline-based regimens has been associated with cardiac toxicity. We wanted to evaluate the efficacy and safety of a new nonanthracycline regimen with trastuzumab. M...

Subject

Medicine

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