Spironolactone for heart failure with preserved ejection fraction.

Pitt, B.; Pfeffer, M.; Assmann, S.; Boineau, R.; Anand, I.; Claggett, Brian; Clausell, N.; S. Desai, Akshay; Diaz, R.; Fleg, J.; Gordeev, I.; Harty, B.; Heitner, J.; Kenwood, C.; Lewis, E.; O’Meara, E.; Probstfield, J.; Shaburishvili, T.; J. Shah, Sanjiv; Solomon, S.; Sweitzer, N.; Yang, Song; Mckinlay, S.

doi:10.1056/NEJMoa1313731

Public

Spironolactone for heart failure with preserved ejection fraction.

Shared by NobleBlocks on Apr 9, 2014 • 12:00 AM UTC

Authors:

B. Pitt

M. Pfeffer

S. Assmann

Abstract

BACKGROUND Mineralocorticoid-receptor antagonists improve the prognosis for patients with heart failure and a reduced left ventricular ejection fraction. We evaluated the effects of spironolactone in patients with heart failure and a preserved left ventricular ejection fraction. METHODS In this rand...

Subject

Medicine

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