The influence of finasteride on the development of prostate cancer.

M. Thompson, Ian; Goodman, P.; Tangen, C.; Lucia, M.; Miller, G.; G. Ford, Leslie; M. Lieber, Michael; Cespedes, R.; Atkins, J.; Lippman, S.; M. Carlin, Susie; M. Ryan, Anne; M Szczepanek, Connie; J. Crowley, John; Coltman, C.

doi:10.1056/NEJMOA030660

Public

The Influence of Finasteride on the Development of Prostate Cancer

Shared by NobleBlocks on Jul 16, 2003 • 12:00 AM UTC

Authors:

Ian M. Thompson

Phyllis J. Goodman

Catherine M. Tangen

Abstract

BACKGROUND: Androgens are involved in the development of prostate cancer. Finasteride, an inhibitor of 5alpha-reductase, inhibits the conversion of testosterone to dihydrotestosterone, the primary androgen in the prostate, and may reduce the risk of prostate cancer. METHODS: In the Prostate Cancer P...

Subject

Finasteride

Medicine

Rectal examination

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