Neoadjuvant chemotherapy or primary surgery in stage IIIC or IV ovarian cancer.

Vergote, Ignace; G Tropé, Claes; Amant, Frédéric; B Kristensen, Gunnar; Ehlen, Tom; Johnson, Nick; H M Verheijen, René; E L van der Burg, Maria; J Lacave, Angel; Benedetti Panici, Pierluigi; G Kenter, Gemma; Casado, Antonio; Mendiola, Cesar; Coens, Corneel; Verleye, Leen; C E Stuart, Gavin; Pecorelli, Sergio; S Reed, Nick; Organization for Research and Treatment of Cancer-Gynaecological Cancer Group, European; Clinical Trials Group, NCIC

doi:10.1056/NEJMoa0908806

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Neoadjuvant chemotherapy or primary surgery in stage IIIC or IV ovarian cancer.

Shared by NobleBlocks on Sep 2, 2010 • 12:00 AM UTC

Authors:

Ignace Vergote

Claes G Tropé

Frédéric Amant

Abstract

BACKGROUND: Primary debulking surgery before initiation of chemotherapy has been the standard of care for patients with advanced ovarian cancer. METHODS: We randomly assigned patients with stage IIIC or IV epithelial ovarian carcinoma, fallopian-tube carcinoma, or primary peritoneal carcinoma to pri...

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