Trial of Tocilizumab in Giant-Cell Arteritis.

H Stone, John; Tuckwell, Katie; Dimonaco, Sophie; Klearman, Micki; Aringer, Martin; Blockmans, Daniel; Brouwer, Elisabeth; C Cid, Maria; Dasgupta, Bhaskar; Rech, Juergen; Salvarani, Carlo; Schett, Georg; Schulze-Koops, Hendrik; Spiera, Robert; H Unizony, Sebastian; Collinson, Neil

doi:10.1056/NEJMoa1613849

Public

Trial of Tocilizumab in Giant-Cell Arteritis.

Shared by NobleBlocks on Jul 27, 2017 • 12:00 AM UTC

Authors:

John H Stone

Katie Tuckwell

Sophie Dimonaco

Abstract

BACKGROUND: Giant-cell arteritis commonly relapses when glucocorticoids are tapered, and the prolonged use of glucocorticoids is associated with side effects. The effect of the interleukin-6 receptor alpha inhibitor tocilizumab on the rates of relapse during glucocorticoid tapering was studied in pa...

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