Sunitinib Alone or after Nephrectomy in Metastatic Renal-Cell Carcinoma.

Méjean, Arnaud; Ravaud, Alain; Thezenas, Simon; Colas, Sandra; Beauval, Jean-Baptiste; Bensalah, Karim; Geoffrois, Lionnel; Thiery-Vuillemin, Antoine; Cormier, Luc; Lang, Hervé; Guy, Laurent; Gravis, Gwenaelle; Rolland, Frederic; Linassier, Claude; Lechevallier, Eric; Beisland, Christian; Aitchison, Michael; Oudard, Stephane; Patard, Jean-Jacques; Theodore, Christine; Chevreau, Christine; Laguerre, Brigitte; Hubert, Jacques; Gross-Goupil, Marine; Bernhard, Jean-Christophe; Albiges, Laurence; Timsit, Marc-Olivier; Lebret, Thierry; Escudier, Bernard

doi:10.1056/NEJMoa1803675

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Sunitinib Alone or after Nephrectomy in Metastatic Renal-Cell Carcinoma.

Shared by NobleBlocks on Aug 2, 2018 • 12:00 AM UTC

Authors:

Arnaud Méjean

Alain Ravaud

Simon Thezenas

Abstract

BACKGROUND: Cytoreductive nephrectomy has been the standard of care in metastatic renal-cell carcinoma for 20 years, supported by randomized trials and large, retrospective studies. However, the efficacy of targeted therapies has challenged this standard. We assessed the role of nephrectomy in patie...

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