Thrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of Stroke.

Ma, Henry; C V Campbell, Bruce; W Parsons, Mark; Churilov, Leonid; R Levi, Christopher; Hsu, Chung; J Kleinig, Timothy; Wijeratne, Tissa; Curtze, Sami; M Dewey, Helen; Miteff, Ferdinand; Tsai, Chon-Haw; Lee, Jiunn-Tay; G Phan, Thanh; Mahant, Neil; Sun, Mu-Chien; Krause, Martin; Sturm, Jonathan; Grimley, Rohan; Chen, Chih-Hung; Hu, Chaur-Jong; A Wong, Andrew; Field, Deborah; Sun, Yu; Alan Barber, P; Sabet, Arman; Jannes, Jim; Jeng, Jiann-Shing; Clissold, Benjamin; Markus, Romesh; Lin, Ching-Huang; Lien, Li-Ming; F Bladin, Christopher; Christensen, Søren; Yassi, Nawaf; Sharma, Gagan; Bivard, Andrew; M Desmond, Patricia; Yan, Bernard; J Mitchell, Peter; Thijs, Vincent; Carey, Leeanne; Meretoja, Atte; M Davis, Stephen; A Donnan, Geoffrey; Investigators, EXTEND

doi:10.1056/NEJMoa1813046

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Thrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of Stroke.

Shared by NobleBlocks on May 9, 2019 • 12:00 AM UTC

Authors:

Henry Ma

Bruce C V Campbell

Mark W Parsons

Abstract

BACKGROUND: The time to initiate intravenous thrombolysis for acute ischemic stroke is generally limited to within 4.5 hours after the onset of symptoms. Some trials have suggested that the treatment window may be extended in patients who are shown to have ischemic but not yet infarcted brain tissue...

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