Angiotensin-Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction.

D Solomon, Scott; J V McMurray, John; S Anand, Inder; Ge, Junbo; S P Lam, Carolyn; P Maggioni, Aldo; Martinez, Felipe; Packer, Milton; A Pfeffer, Marc; Pieske, Burkert; M Redfield, Margaret; L Rouleau, Jean; J van Veldhuisen, Dirk; Zannad, Faiez; R Zile, Michael; S Desai, Akshay; Claggett, Brian; S Jhund, Pardeep; A Boytsov, Sergey; Comin-Colet, Josep; Cleland, John; Düngen, Hans-Dirk; Goncalvesova, Eva; Katova, Tzvetana; F Kerr Saraiva, Jose; Lelonek, Małgorzata; Merkely, Bela; Senni, Michele; J Shah, Sanjiv; Zhou, Jingmin; R Rizkala, Adel; Gong, Jianjian; C Shi, Victor; P Lefkowitz, Martin; Investigators and Committees, PARAGON-HF

doi:10.1056/NEJMoa1908655

Public

Angiotensin-Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction.

Shared by NobleBlocks on Oct 24, 2019 • 12:00 AM UTC

Authors:

Scott D Solomon

John J V McMurray

Inder S Anand

Abstract

BACKGROUND: The angiotensin receptor-neprilysin inhibitor sacubitril-valsartan led to a reduced risk of hospitalization for heart failure or death from cardiovascular causes among patients with heart failure and reduced ejection fraction. The effect of angiotensin receptor-neprilysin inhibition in p...

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