A powerful nonviral vector for in vivo gene transfer into the adult mammalian brain: polyethylenimine.

B, Abdallah; A, Hassan; C, Benoist; D, Goula; JP, Behr; BA, Demeneix

doi:10.1089/hum.1996.7.16-1947

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A powerful nonviral vector for in vivo gene transfer into the adult mammalian brain: polyethylenimine.

Shared by NobleBlocks on Oct 1, 1996 • 12:00 AM UTC

Authors:

Abdallah B

Hassan A

Benoist C

Abstract

Nonviral gene transfer into the central nervous system (CNS) offers the prospect of providing safe therapies for neurological disorders and manipulating gene expression for studying neuronal function. However, results reported so far have been disappointing. We show that the cationic polymer polyeth...

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