Plasma levels of C-type lectin REG3α and gut damage in people with HIV.

Isnard, S.; Ramendra, R.; P. Dupuy, F.; Lin, John; Fombuena, B.; Kokinov, N.; Kema, I.; Jenabian, Mohammad-Ali; Lebouchẻ, B.; Costiniuk, C.; Ancuța, P.; Bernard, N.; Silverman, M.; Lakatos, P.; Durand, Madeleine; Tremblay, C.; Routy, J.

doi:10.1093/INFDIS/JIZ423

Public

Plasma levels of C-type lectin REG3α and gut damage in people with HIV.

Shared by NobleBlocks on Aug 23, 2019 • 12:00 AM UTC

Authors:

S. Isnard

R. Ramendra

F. P. Dupuy

Abstract

BACKGROUND Regenerating islet-derived protein-3α (REG3α) is an antimicrobial peptide secreted by intestinal Paneth cells. Circulating REG3α has been identified as a gut damage marker in inflammatory bowel diseases. People with HIV (PWH) on antiretroviral therapy (ART) present with an abnormal intest...

Subject

Medicine

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