Transcription-mediated replication hindrance: a major driver of genome instability
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Shared by NobleBlocks on May 23, 2019 • 12:00 AM UTC
Authors:
Belén Gómez‐González
,
A. Aguilera
Abstract
In this review, Gómez-González et al. discuss the underlying causes of transcription–replication conflicts, which are major threats to genome integrity. They also discuss mechanisms by which cells resolve these conflicts to sustain genome integrity.
