AmpD, essential for both β‐lactamase regulation and cell wall recycling, is a novel cytosolic <i>N</i>‐acetylmuramyl‐L‐alanine amidase

Jacobs, Christine; Joris, Bernard; Jamin, Marc; Klarsov, Klaus; van Beeumen, Jozef; Mengin‐Lecreulx, Dominique; van Heijenoort, Jean; T. Park, James; Normark, Staffan; Frère, Jean‐Marie

doi:10.1111/j.1365-2958.1995.tb02268.x

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AmpD, essential for both β‐lactamase regulation and cell wall recycling, is a novel cytosolic N‐acetylmuramyl‐L‐alanine amidase

Shared by NobleBlocks on Feb 1, 1995 • 12:00 AM UTC

Authors:

Christine Jacobs

Bernard Joris

Marc Jamin

Abstract

Summary In enterobacteria, the ampD gene encodes a cytosolic protein which acts as a negative regulator of β‐lactamase expression. It is shown here that the AmpD protein is a novel N ‐acetylmuramyl‐L‐alanine amidase (E.C.3.5.1.28) participating in the intracellular recycling of peptido‐glycan fragme...

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