Occurrence of beta-methylamino-l-alanine (BMAA) in ALS/PDC patients from Guam.

SJ, Murch; PA, Cox; SA, Banack; JC, Steele; OW, Sacks

doi:10.1111/j.1600-0404.2004.00320.x

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Occurrence of beta-methylamino-l-alanine (BMAA) in ALS/PDC patients from Guam.

Shared by NobleBlocks on Oct 1, 2004 • 12:00 AM UTC

Authors:

Murch SJ

Cox PA

Banack SA

Abstract

We tested the brain tissues of the Chamorro people of Guam who died of amyotrophic lateral sclerosis/Parkinsonism dimentia complex (ALS/PDC) for the neurotoxin beta-methylamino-l-alanine (BMAA). We used validated high-pressure liquid chromatography and liquid chromatography-mass spectrometry analyse...

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