Lattice light-sheet microscopy: Imaging molecules to embryos at high spatiotemporal resolution

Chen, Bi-Chang; R. Legant, Wesley; Wang, Kai; Shao, Lin; E. Milkie, Daniel; W. Davidson, Michael; Janetopoulos, Chris; S. Wu, Xufeng; A. Hammer, John; Liu, Zhe; P. English, Brian; Mimori-Kiyosue, Yuko; P. Romero, Daniel; T. Ritter, Alex; Lippincott-Schwartz, Jennifer; Fritz-Laylin, Lillian; Dyche Mullins, R.; M. Mitchell, Diana; N. Bembenek, Joshua; Reymann, Anne-Cecile; Böhme, Ralph; W. Grill, Stephan; T. Wang, Jennifer; Seydoux, Geraldine; Serdar Tulu, U.; P. Kiehart, Daniel; Betzig, Eric

doi:10.1126/science.1257998

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Lattice light-sheet microscopy: Imaging molecules to embryos at high spatiotemporal resolution

Shared by NobleBlocks on Oct 24, 2014 • 12:00 AM UTC

Authors:

Bi-Chang Chen

Wesley R. Legant

Kai Wang

Abstract

From single molecules to embryos in living color Animation defines life, and the three-dimensional (3D) imaging of dynamic biological processes occurring within living specimens is essential to understand life. However, in vivo imaging, especially in 3D, involves inevitable tradeoffs of resolution, ...

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