Studies of the HER-2/
            <i>neu</i>
            Proto-Oncogene in Human Breast and Ovarian Cancer

J. Slamon, Dennis; Godolphin, William; A. Jones, Lovell; A. Holt, John; G. Wong, Steven; E. Keith, Duane; J. Levin, Wendy; G. Stuart, Susan; Udove, Judy; Ullrich, Axel; F. Press, Michael

doi:10.1126/science.2470152

Public

Studies of the HER-2/ neu Proto-Oncogene in Human Breast and Ovarian Cancer

Shared by NobleBlocks on May 12, 1989 • 12:00 AM UTC

Authors:

Dennis J. Slamon

William Godolphin

Lovell A. Jones

Abstract

Carcinoma of the breast and ovary account for one-third of all cancers occurring in women and together are responsible for approximately one-quarter of cancer-related deaths in females. The HER-2/ neu proto-oncogene is amplified in 25 to 30 percent of human primary breast cancers and this alteration...

Discussions