Paracellin-1, a renal tight junction protein required for paracellular Mg2+ resorption.

DB, Simon; Y, Lu; KA, Choate; H, Velazquez; E, Al-Sabban; M, Praga; G, Casari; A, Bettinelli; G, Colussi; J, Rodriguez-Soriano; D, McCredie; D, Milford; S, Sanjad; RP, Lifton

doi:10.1126/science.285.5424.103

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Paracellin-1, a renal tight junction protein required for paracellular Mg2+ resorption.

Shared by NobleBlocks on Jul 1, 1999 • 12:00 AM UTC

Authors:

Simon DB

Lu Y

Choate KA

Abstract

Epithelia permit selective and regulated flux from apical to basolateral surfaces by transcellular passage through cells or paracellular flux between cells. Tight junctions constitute the barrier to paracellular conductance; however, little is known about the specific molecules that mediate paracell...

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