Emergence and spread of a human-transmissible multidrug-resistant nontuberculous mycobacterium.

JM, Bryant; DM, Grogono; D, Rodriguez-Rincon; I, Everall; KP, Brown; P, Moreno; D, Verma; E, Hill; J, Drijkoningen; P, Gilligan; CR, Esther; PG, Noone; O, Giddings; SC, Bell; R, Thomson; CE, Wainwright; C, Coulter; S, Pandey; ME, Wood; RE, Stockwell; KA, Ramsay; LJ, Sherrard; TJ, Kidd; N, Jabbour; GR, Johnson; LD, Knibbs; L, Morawska; PD, Sly; A, Jones; D, Bilton; I, Laurenson; M, Ruddy; S, Bourke; IC, Bowler; SJ, Chapman; A, Clayton; M, Cullen; T, Daniels; O, Dempsey; M, Denton; M, Desai; RJ, Drew; F, Edenborough; J, Evans; J, Folb; H, Humphrey; B, Isalska; S, Jensen-Fangel; B, Jönsson; AM, Jones; TL, Katzenstein; T, Lillebaek; G, MacGregor; S, Mayell; M, Millar; D, Modha; EF, Nash; C, O'Brien; D, O'Brien; C, Ohri; CS, Pao; D, Peckham; F, Perrin; A, Perry; T, Pressler; L, Prtak; T, Qvist; A, Robb; H, Rodgers; K, Schaffer; N, Shafi; Ingen J, van; M, Walshaw; D, Watson; N, West; J, Whitehouse; CS, Haworth; SR, Harris; D, Ordway; J, Parkhill; RA, Floto

doi:10.1126/science.aaf8156

Public

Emergence and spread of a human-transmissible multidrug-resistant nontuberculous mycobacterium.

Shared by NobleBlocks on Nov 1, 2016 • 12:00 AM UTC

Authors:

Bryant JM

Grogono DM

Rodriguez-Rincon D

Abstract

Lung infections with Mycobacterium abscessus, a species of multidrug-resistant nontuberculous mycobacteria, are emerging as an important global threat to individuals with cystic fibrosis (CF), in whom M. abscessus accelerates inflammatory lung damage, leading to increased morbidity and mortality. Pr...

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