Mismatch repair status and BRAF mutation status in metastatic colorectal cancer patients: a pooled analysis of the CAIRO, CAIRO2, COIN and FOCUS studies

Venderbosch, S.; Nagtegaal, I.; Maughan, T.; G. Smith, Christopher; Cheadle, J.; Fisher, D.; Kaplan, R.; Quirke, P.; Seymour, M.; Richman, S.; Meijer, G.; Ylstra, B.; Heideman, D.; D. de Haan, A.; Punt, C.; Koopman, M.

doi:10.1158/1078-0432.CCR-14-0332

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Mismatch repair status and BRAF mutation status in metastatic colorectal cancer patients: a pooled analysis of the CAIRO, CAIRO2, COIN and FOCUS studies

Shared by NobleBlocks on Aug 19, 2014 • 12:00 AM UTC

Authors:

S. Venderbosch

I. Nagtegaal

T. Maughan

Abstract

Purpose: To determine the prevalence and prognostic value of mismatch repair (MMR) status and its relation to BRAF mutation (BRAFMT) status in metastatic colorectal cancer (mCRC). Experimental Design: A pooled analysis of four phase III studies in first-line treatment of mCRC (CAIRO, CAIRO2, COIN, a...

Subject

Medicine

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