The Genomic Landscape of SMARCA4 Alterations and Associations with Outcomes in Patients with Lung Cancer

Schoenfeld, A.; Bandlamudi, C.; Lavery, J.; Montecalvo, J.; Namakydoust, A.; Rizvi, H.; Egger, J.; P. Concepcion, Carla; Paul, S.; Arcila, M.; Daneshbod, Y.; C. Chang, Jason; Sauter, J.; Beras, A.; Ladanyi, M.; Jacks, T.; Rudin, C.; Taylor, B.; Donoghue, M.; Heller, G.; Hellmann, M.; Rekhtman, N.; Riely, Gregory

doi:10.1158/1078-0432.CCR-20-1825

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The Genomic Landscape of SMARCA4 Alterations and Associations with Outcomes in Patients with Lung Cancer

Shared by NobleBlocks on Jul 24, 2020 • 12:00 AM UTC

Authors:

A. Schoenfeld

C. Bandlamudi

J. Lavery

Abstract

Purpose: SMARCA4 mutations are among the most common recurrent alterations in non–small cell lung cancer (NSCLC), but the relationship to other genomic abnormalities and clinical impact has not been established. Experimental Design: To characterize SMARCA4 alterations in NSCLC, we analyzed the genom...

Subject

Medicine

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