High-Throughput Genomics and Clinical Outcome in Hard-to-Treat Advanced Cancers: Results of the MOSCATO 01 Trial.

Massard, Christophe; Michiels, Stefan; Ferté, Charles; Le Deley, Marie-Cécile; Lacroix, Ludovic; Hollebecque, Antoine; Verlingue, Loic; Ileana, Ecaterina; Rosellini, Silvia; Ammari, Samy; Ngo-Camus, Maud; Bahleda, Rastislav; Gazzah, Anas; Varga, Andrea; Postel-Vinay, Sophie; Loriot, Yohann; Even, Caroline; Breuskin, Ingrid; Auger, Nathalie; Job, Bastien; De Baere, Thierry; Deschamps, Frederic; Vielh, Philippe; Scoazec, Jean-Yves; Lazar, Vladimir; Richon, Catherine; Ribrag, Vincent; Deutsch, Eric; Angevin, Eric; Vassal, Gilles; Eggermont, Alexander; André, Fabrice; Soria, Jean-Charles

doi:10.1158/2159-8290.CD-16-1396

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High-Throughput Genomics and Clinical Outcome in Hard-to-Treat Advanced Cancers: Results of the MOSCATO 01 Trial.

Shared by NobleBlocks on Jun 1, 2017 • 12:00 AM UTC

Authors:

Christophe Massard

Stefan Michiels

Charles Ferté

Abstract

High-throughput genomic analyses may improve outcomes in patients with advanced cancers. MOSCATO 01 is a prospective clinical trial evaluating the clinical benefit of this approach. Nucleic acids were extracted from fresh-frozen tumor biopsies and analyzed by array comparative genomic hybridization,...

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