Comparison of Vancomycin Area-Under-the-Curve Dosing Versus Trough Target-Based Dosing in Obese and Nonobese Patients With Methicillin-Resistant <i>Staphylococcus aureus</i> Bacteremia.

JR, Covvey; O, Erickson; D, Fiumara; K, Mazzei; Z, Moszczenski; K, Slipak; BD, Nemecek; DE, Zimmerman; AJ, Guarascio

doi:10.1177/1060028019897100

Public

Comparison of Vancomycin Area-Under-the-Curve Dosing Versus Trough Target-Based Dosing in Obese and Nonobese Patients With Methicillin-Resistant Staphylococcus aureus Bacteremia.

Shared by NobleBlocks on Dec 30, 2019 • 12:00 AM UTC

Authors:

Covvey JR

Erickson O

Fiumara D

Abstract

Background: A vancomycin target of area under the curve to minimum inhibitory concentration (AUC:MIC) ratio ≥400 is recommended for treatment of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia. Objective: To evaluate vancomycin total daily dose (TDD) achieving trough targets versus a c...

Subject

Obesity

Vancomycin

therapeutic drug monitoring

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