Efficacy of L-asparaginase with methotrexate and dexamethasone (AspaMetDex regimen) in patients with refractory or relapsing extranodal NK/T-cell lymphoma, a phase 2 study.

A, Jaccard; N, Gachard; B, Marin; S, Rogez; M, Audrain; F, Suarez; H, Tilly; F, Morschhauser; C, Thieblemont; L, Ysebaert; A, Devidas; B, Petit; Leval L, de; P, Gaulard; J, Feuillard; D, Bordessoule; O, Hermine

doi:10.1182/blood-2010-09-307454

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Efficacy of L-asparaginase with methotrexate and dexamethasone (AspaMetDex regimen) in patients with refractory or relapsing extranodal NK/T-cell lymphoma, a phase 2 study.

Shared by NobleBlocks on Dec 1, 2010 • 12:00 AM UTC

Authors:

Jaccard A

Gachard N

Marin B

Abstract

Extranodal NK/T-cell lymphoma, nasal type, is a rare and highly aggressive disease with a grim prognosis. No therapeutic strategy is currently identified in relapsing patients. We report the results of a French prospective phase II trial of an L-asparaginase-containing regimen in 19 patients with re...

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