Th1 and Th17 hypercytokinemia as early host response signature in severe pandemic influenza

Bermejo-Martín, J.; Ortiz de Lejarazu, R.; Pumarola, T.; Rello, J.; Almansa, R.; Ramírez, P.; Martín-Loeches, I.; Varillas, D.; C. Gallegos, M.; Serón, C.; Micheloud, D.; Gomez, JoséManuel; Tenorio-Abreu, A.; J. Ramos, M.; Molina, MLourdes; Huidobro, S.; Sánchez, E.; Gordon, M.; Fernández, Victoria; del Castillo, A.; Marcos, M.; Villanueva, Beatriz; López, C.; Rodríguez-Domínguez, M.; Galán, J.; Cantón, R.; Lietor, A.; Rojo, S.; Eiros, J.; Hinojosa, C.; González, I.; Torner, N.; Banner, D.; León, A.; Cuesta, P.; Rowe, T.; Kelvin, D.

doi:10.1186/cc8208

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Th1 and Th17 hypercytokinemia as early host response signature in severe pandemic influenza

Shared by NobleBlocks on Dec 11, 2009 • 12:00 AM UTC

Authors:

J. Bermejo-Martín

R. Ortiz de Lejarazu

T. Pumarola

Abstract

IntroductionHuman host immune response following infection with the new variant of A/H1N1 pandemic influenza virus (nvH1N1) is poorly understood. We utilize here systemic cytokine and antibody levels in evaluating differences in early immune response in both mild and severe patients infected with nv...

Subject

Medicine

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