Intranasal delivery of chitosan-DNA vaccine generates mucosal SIgA and anti-CVB3 protection.

W, Xu; Y, Shen; Z, Jiang; Y, Wang; Y, Chu; S, Xiong

doi:10.1016/j.vaccine.2004.03.033

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Intranasal delivery of chitosan-DNA vaccine generates mucosal SIgA and anti-CVB3 protection.

Shared by NobleBlocks on Sep 1, 2004 • 12:00 AM UTC

Authors:

Xu W

Shen Y

Jiang Z

Abstract

Coxsackievirus B3 infections are common causes of acute and chronic myocarditis with no effective prophylactic treatment available. We describe here a prophylactic strategy using chitosan-DNA intranasal immunization to induce CVB3 specific immune responses. Intranasal administration with chitosan-DN...

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