The effect of nucleus pulposus crosslinking and glycosaminoglycan degradation on disc mechanical function.

CS, Yerramalli; AI, Chou; GJ, Miller; SB, Nicoll; KR, Chin; DM, Elliott

doi:10.1007/s10237-006-0043-0

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The effect of nucleus pulposus crosslinking and glycosaminoglycan degradation on disc mechanical function.

Published in Biomechanics and modeling in mechanobiology • May 20, 2006

Authors:

Yerramalli CS

Chou AI

Miller GJ

Abstract

Altered mechanical loading, secondary to biochemical changes in the nucleus pulposus, is a potential mechanism in disc degeneration. An understanding of the role of this altered mechanical loading is only possible by separating the mechanical and biological effects of early nucleus pulposus changes....

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