Combined analysis of intratumoral human equilibrative nucleoside transporter 1 (hENT1) and ribonucleotide reductase regulatory subunit M1 (RRM1) expression is a powerful predictor of survival in patients with pancreatic carcinoma treated with adjuvant gemcitabine-based chemotherapy after operative resection.

N, Nakagawa; Y, Murakami; K, Uemura; T, Sudo; Y, Hashimoto; N, Kondo; T, Sueda

doi:10.1016/j.surg.2012.10.010

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Combined analysis of intratumoral human equilibrative nucleoside transporter 1 (hENT1) and ribonucleotide reductase regulatory subunit M1 (RRM1) expression is a powerful predictor of survival in patients with pancreatic carcinoma treated with adjuvant gemcitabine-based chemotherapy after operative resection.

Shared by NobleBlocks on Dec 17, 2012 • 12:00 AM UTC

Authors:

Nakagawa N

Murakami Y

Uemura K

Abstract

<h4>Background</h4>Although postoperative adjuvant chemotherapy for pancreatic carcinoma improves survival in some patients, its efficacy varies among individuals. The aim of this study was to determine the usefulness of intratumoral expression of human equilibrative nucleoside transporter 1 (hENT1)...

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