Serine Proteases Decrease Intestinal Epithelial Permeability By A PKCζ‐mediated mechanism
Published in The FASEB Journal • Apr 1, 2007
NobleIDNI7P96W07R78S86
Authors:,
Veronica A. Swystun
Wallace K. MacNaughton
Abstract
The transport of ions and the permeability to macromolecules across the epithelium regulates fluid balance in the gastrointestinal tract. The digestive serine proteases trypsin, elastase and chymotrypsin decrease the paracellular permeability of intestinal epithelial cells to Na + , Cl − and 3000MW ...
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