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The solid state

Published in Informa Healthcare eBooks • May 1, 2009
NobleIDNI5P54W30R62S97
Authors:
Alastair J. Florence
,
Alexander T. Florence
,
Juergen Siepmann

Abstract

Many active pharmaceutical ingredients (APIs) can exist in more than one solid-state form, including crystalline polymorphs, solvates, salts, cocrystals, and noncrystalline or amorphous solids (Fig. 1; Table 1). Hence, assessment and control of the solid-state structure of APIs is necessary to ensur...

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