Selective accumulation of MyoD and myogenin mRNAs in fast and slow adult skeletal muscle is controlled by innervation and hormones.

SM, Hughes; JM, Taylor; SJ, Tapscott; CM, Gurley; WJ, Carter; CA, Peterson

doi:10.1242/dev.118.4.1137

Public

Selective accumulation of MyoD and myogenin mRNAs in fast and slow adult skeletal muscle is controlled by innervation and hormones.

Shared by NobleBlocks on Aug 1, 1993 • 12:00 AM UTC

Authors:

Hughes SM

Taylor JM

Tapscott SJ

Abstract

Each of the myogenic helix-loop-helix transcription factors (MyoD, Myogenin, Myf-5, and MRF4) is capable of activating muscle-specific gene expression, yet distinct functions have not been ascribed to the individual proteins. We report here that MyoD and Myogenin mRNAs selectively accumulate in hind...

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