Hypericin-Induced Cell Photosensitization Involves an Intracellular pH Decrease
Published in Journal of the American Chemical Society • Jan 1, 1996
NobleIDNI2P26W36R74S46
Authors:,,
Franck Sureau
Pavol Miškovský
L. Chinsky
Abstract
Snarf-1-AM (Seminaphthorhodafluor-1-acetoxymethylester) being used as a fluorescent pH probe, confocal laser microspectrofluorometric measurements allowed intracellular pH to be assessed within 3T3 mouse fibroblasts in the presence or in the absence of hypericin. Cytoplasmic local pH drops of 0.4 un...
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