Less stimulating environmental conditions decrease spatial learning ability and reduce GAP-43 and synaptophysin immunostaining in the hippocampal formation in adult male mice
Published in Kobe University Repository Kernel (Kobe University) • Jan 1, 2009
NobleIDNI2P19W20R84S34
Authors:,,
Mitsuru Miyamoto
Kozo Sugioka
Takamitsu Arakawa
Abstract
Environmental conditions affect learning ability and cause neuroanatomical alterations of neurons and synapses in the hippocampal formation. We reared male mice in standard, enriched and wheel-running environments (n = 7 in each group) as well as in an impoverished environment (n = 9) for 102 days a...
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