Isoflurane Exposure did not Adversely Affect Recognition Memory or Decrease Hippocampal Brain Derived Neurotrophic Factor Expression in the 17 Day Old Rat Pup
Published in Journal of Anesthesia & Clinical Research • Jan 1, 2013
Authors:
Michelle E Schober Benjamin Block
Abstract
A previous study showed that hippocampal BDNF mRNA decreased in 17 day old (D17) rats, relative to agematched naive rats, at day 1, 3, 7 and 14 after sham surgery in a traumatic brain injury model. The anesthetic isoflurane activates GABA and inhibits NMDA receptor currents, both of which are known ...
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