Solitary chemosensory cells and chemosensory brush cells: taste cell-like airway chemosensors

The airway is replete with solitary chemosensory cells (SCCs) and brush cells (BCs) that can trigger inflammation and chemesthesis. These chemosensors utilize the canonical "bitter" taste transduction cascade (T2Rs, αgustducin, TRPM5) to detect bitter substances and bacterial metabolites. Taste cell... View More