Mechanisms involved in sulfur mustard analogs'-induced DNA damage and skin toxicity

Sulfur mustard (2,2-dichlorodiethyl sulfide; SM), a bifunctional alkylating chemical warfare agent, forms adducts and crosslinks with DNA, RNA and proteins. 2-Chloroethyl ethyl sulfide (CEES), a monofunctional alkylating agent, and nitrogen mustard [bis(2-chloroethyl)methylamine; NM] a bifunctional ... View More