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Published in Critical Care Medicine • Dec 1, 2012
NobleIDNI3P163W951R943S219
Authors:
André C. Kalil
,
Diana F. Florescu

Abstract

Introduction: Despite same sponsor, same treatment with recombinant human activated protein C, and same placebo-controlled study design, the negative results from PROWESS-SHOCK trial contradicted the positive results, i.e. survival benefit, observed with the original PROWESS trial. Hypothesis: We hy...

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