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The dual roles of DNA-PKcs, NBS1, and TRF2 proteins in DNA repair and telomere end-capping

Published in Colorado State University • Jan 1, 2007
NobleIDNI9P62W48R90S76
Authors:
Eli Stowe Williams
,
Robert L. Ullrich
,
Susan M. Bailey

Abstract

Telomeres are the nucleoprotein structures located at the ends of linear chromosomes that distinguish naturally occurring chromosome ends from DNA double-strand breaks (DSBs). The ability to properly distinguish telomeres as such is critical to long term cellular survival as failure to do so can res...

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