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CD177+ neutrophils as functionally activated neutrophils negatively regulate IBD.

Published in Gut • Jun 1, 2018
Authors:
Guangxi Zhou
,
Lin Yu
,
Leilei Fang

Abstract

BACKGROUND: Neutrophils are accumulated in inflamed mucosa of IBD and play an important role in the pathogenesis. CD177 is expressed in neutrophils specifically and upregulated during inflammation. However, the role of CD177+ neutrophils in pathogenesis of IBD remains elusive. MATERIALS AND METHODS:...

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