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ОПРЕДЕЛЕНИЕ ПОКАЗАТЕЛЕЙ КАЧЕСТВА КАПСУЛИРОВАННОЙ ЛЕКАРСТВЕННОЙ ФОРМЫ С ЭКСТРАКТОМ ТРАВЫ КРАПИВЫ КОНОПЛЕВОЙ СУХИМ

Федосеева, Kir'iakova

chemistry of plant raw material20 Jan 2017Open access

NobleIDark:/48914/w1/20260526/1F2BAD44DOI10.14258/jcprm.2017021717

Abstract

Conduct a comprehensive study of the aerial part of the plant genus Urtica (u. dioica, u. cannabina, u. urens), growing in the Altai Territory. Obtain dry extracts of the herbs urticae dioicae, herbs urticae cannabinae, herbs urticae urensis. In the study of the technological properties of the herb Urticae Cannabinae dry established otsyrevaemost high, so there was a need to develop a structure of a capsulated form with the addition of auxiliary substances.Spend the standardization and evaluation of the availability of pharmaceutical capsules with an extract of herb urticae cannabinae dry. Defined quality indicators capsules: description, authenticity (identified: chlorogenic acid, shaftozid, rutin, robinin, kvertsitrin, flavonoid structure of apigenin). The quantitative content of flavonoids in terms kvertsitrin was – 2,05 ± 0,04%. Established pharmaceutical availability capsules: capsules disintegration less than 20 min, more than 70% dissolution.These quality indicators are used to develop the draft regulatory documents "hard capsules with the extract of herb Urticae Cannabinae dry."

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